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Träfflista för sökning "hsv:(MEDICIN OCH HÄLSOVETENSKAP) hsv:(Klinisk medicin) srt2:(1990-1999);srt2:(1996);mspu:(conferencepaper)"

Sökning: hsv:(MEDICIN OCH HÄLSOVETENSKAP) hsv:(Klinisk medicin) > (1990-1999) > (1996) > Konferensbidrag

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  • Boström, Ola, 1963, et al. (författare)
  • A new neck injury criterion candidate-based on injury findings in the cervical spinal ganglia after experimental neck extension trauma
  • 1996
  • Ingår i: PROCEEDINGS OF THE 1996 INTERNATIONAL IRCOBI CONFERENCE ON THE BIOMECHANICS OF IMPACT, SEPTEMBER 11-13, DUBLIN, IRELAND. ; , s. 123-136
  • Konferensbidrag (refereegranskat)abstract
    • In this study a mathematical model, based on Navier Stokes equations, was developed and validated against experimental data. This model predicts the pressure changes in the spinal canal as a function of the volume change inside the canal during neck bending in the x-z (sagittal) plane. Another aim of the study was to investigate pressure phenomena and ganglion injuries at static neck extension loading and dynamic neck extension trauma with a head-restraint present. Experiments on pigs were conducted. Preliminary results indicate that ganglion injuries, as well as pressure transients inside the spinal canal, seem to correlate to the phase shift when the neck passes an s-shape (or maximal retraction) during the rearward motion of the head. That is, when the upper neck quickly changes from a flexion to an extension shape. Static loading of the neck resulted in no signs of injuries to the ganglia. A possible candidate for a neck injury criterion is presented, based on the relative acceleration between the top and the bottom of the cervical spine. A tolerance level based on the pig tests is also discussed.
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  • Steen, Stig, et al. (författare)
  • Improvement in lung preservation
  • 1996
  • Ingår i: Compromised perfusion / Mikrozirkulation in Forschung und Klinik. - : S. Karger AG. - 0254-5195. - 9783805562256 - 380556225X ; 22, s. 50-60
  • Konferensbidrag (refereegranskat)
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  • af Klinteberg, C, et al. (författare)
  • Laser-induced fluorescence diagnostics of basal cell carcinomas of the skin following topical ALA application
  • 1996
  • Ingår i: Optical Biopsies and Microscopic Techniques, Proceedings of. - : SPIE. - 0819423289 ; 2926, s. 32-40
  • Konferensbidrag (refereegranskat)abstract
    • Fourteen patients with superficial basal cell carcinomas (BCCs) and fifteen patients with nodular BCCs were investigated by means of laser-induced fluorescence (LIF) in connection with photodynamic therapy (PDT). Topical application of delta-amino levulinic acid (ALA) was performed six hours prior to the treatment session. Fluorescence spectra were recorded, using a point-monitoring system with an excitation wavelength of 405 nm. The measurements were performed in scans over the lesion and the surrounding normal skin before application of ALA, and immediately before and after the laser treatment. The selective uptake of the photosensitiser resulted in a fluorescence intensity ratio of 2.4:1 for superficial BCCs and 2.5:1 for nodular BCCs. If the fluorescence intensity was divided by the autofluorescence, this resulted in a contrast enhancement of about a factor 6 for tumour tissue. In seven patients (five with nodular BCC and two with superficial BCC), additional fluorescence measurements were performed two and four hours following the ALA application, and two hours after the PDT procedure. Thus, the kinetics of the transformation of ACA to protoporphyrin IX (PpIX) could be followed, which indicated that the synthesis of PpIX was more rapid in the tumour than in the normal tissue. After four hours, the PpIX level inside the tumour was saturated, while there still was an accumulation in the surrounding skin. The highest contrast between tumour and normal skin was reached within two hours after the ALA application.
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  • Resultat 1-10 av 13

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