| 1. |
- Agardh, Elisabet, et al.
(författare)
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The prevalence of retinopathy and associated medical risk factors in type I (insulin-dependent) diabetes mellitus
- 1989
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Ingår i: Journal of Internal Medicine. - 1365-2796. ; 226:1, s. 47-52
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Tidskriftsartikel (refereegranskat)abstract
- The prevalence of diabetic retinopathy and the associated medical risk factors, such as age at onset and duration of diabetes, metabolic control, blood pressure, albumin clearance and serum creatinine, were studied in 501 patients with type I diabetes mellitus. The prevalence of retinopathy, characterized as simplex, maculopathy, preproliferative, and proliferative, was 60.5%. Patients with retinopathy were younger at the onset of diabetes, and had a longer duration of disease. In patients with more than 10 years of diabetes, proliferative retinopathy was more frequent if onset was before they were 15 years old, despite the fact that the duration of diabetes did not differ. Patients with severe retinopathy had worse metabolic control, and were more frequently treated for hypertension. In addition, the systolic blood pressure was elevated in all groups of patients with any type of retinopathy, whereas the diastolic blood pressure was elevated only in patients with more severe forms. Patients with severe retinopathy also had higher levels of albumin clearance.
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| 2. |
- Torffvit, Ole, et al.
(författare)
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Exercise stimulation in insulin-dependent diabetics, normal increase in albuminuria with abnormal blood pressure response
- 1987
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Ingår i: Scandinavian Journal of Clinical & Laboratory Investigation. - 1502-7686. ; 47:3, s. 253-259
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Tidskriftsartikel (refereegranskat)abstract
- Increased urinary albumin excretion rate (AER), microalbuminuria, has been regarded as a sign of incipient nephropathy. The influence of exercise on AER was investigated in 10 male type I diabetics and in 12 age-matched male controls. The duration of diabetes was 7-31 years (median 14 years). The exercise tests were performed both as a combined submaximal workload-waterload test and as a maximal workload test. Urinary albumin was measured with an ELISA technique. During exercise in both tests, no difference was seen in the AER between diabetics and their controls. However, the increase in systolic blood pressure was significantly more marked in the diabetics. There was no correlation between the blood pressure response during exercise and the AER, neither in the diabetics, nor in their controls. It is concluded, that, increased blood pressure response during exercise does not necessarily result in increased AER in type I diabetics.
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