Sökning: hsv:(MEDICIN OCH HÄLSOVETENSKAP) hsv:(Klinisk medicin) hsv:(Cancer och onkologi)
> (2015-2019)
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Dual-modality probe...
Dual-modality probe intended for prostate cancer detection combining Raman spectroscopy and tactile resonance technology—discrimination of normal human prostate tissues ex vivo
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- Nyberg, Morgan, 1971- (författare)
- Luleå tekniska universitet,Umeå universitet,Centrum för medicinsk teknik och fysik (CMTF),Dept. of Engineering Sciences and Mathematics, Luleå University of Technology, Luleå, Sweden,Signaler och system,Centre for Biomedical Engineering and Physics (CMTF), Luleå, Umeå, Sweden
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- Jalkanen, Ville, 1978- (författare)
- Umeå universitet,Institutionen för tillämpad fysik och elektronik,Centrum för medicinsk teknik och fysik (CMTF),Centre for Biomedical Engineering and Physics (CMTF), Luleå, Umeå, Sweden; Department of Applied Physics and Electronics, Umeå University, Umeå, Sweden
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- Ramser, Kerstin (författare)
- Luleå tekniska universitet,Umeå universitet,Centrum för medicinsk teknik och fysik (CMTF),Dept. of Engineering Sciences and Mathematics, Luleå University of Technology, Luleå, Sweden,Strömningslära och experimentell mekanik,Centre for Biomedical Engineering and Physics (CMTF), Luleå, Umeå, Sweden
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- Ljungberg, Börje (författare)
- Umeå universitet,Urologi och andrologi,Njurcancer,Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå Univeristy, Umeå, Sweden
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- Bergh, Anders (författare)
- Umeå universitet,Patologi,Department of Medical Bioscience, Pathology, Umeå Univeristy, Umeå, Sweden
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- Lindahl, Olof A. (författare)
- Umeå universitet,Radiofysik,Centrum för medicinsk teknik och fysik (CMTF),Dept. of Engineering Sciences and Mathematics, Luleå University of Technology, Luleå, Sweden,Department of Radiation Sciences, Umeå University, Umeå, Sweden
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(creator_code:org_t)
- 2015-03-12
- 2015
- Engelska.
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Ingår i: Journal of Medical Engineering & Technology. - : Taylor & Francis. - 0309-1902 .- 1464-522X. ; 39:3, s. 198-207
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Prostate cancer is the most common cancer for men in the western world. For the first time, a dual-modality probe, combining Raman spectroscopy and tactile resonance technology, has been used for assessment of fresh human prostate tissue. The study investigates the potential of the dual-modality probe by testing its ability to differentiate prostate tissue types ex vivo. Measurements on four prostates show that the tactile resonance modality was able to discriminate soft epithelial tissue and stiff stroma (p<0.05). The Raman spectra exhibited a strong fluorescent background at the current experimental settings. However, stroma could be discerned from epithelia by integrating the value of the spectral background. Combining both parameters by a stepwise analysis resulted in 100% sensitivity and 91% specificity. Although no cancer tissue was analysed, the results are promising for further development of the instrument and method for discriminating prostate tissues and cancer.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Maskinteknik -- Teknisk mekanik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Mechanical Engineering -- Applied Mechanics (hsv//eng)
Nyckelord
- Prostate cancer
- radical prostatectomy
- raman spectroscopy
- tactile resonance technology
- tissue autofluorescence
- Experimentell mekanik
- Centre - Centre for Biomedical Engineering and Physics (CMTF)
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