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Träfflista för sökning "hsv:(MEDICIN OCH HÄLSOVETENSKAP) hsv:(Klinisk medicin) hsv:(Pediatrik) ;pers:(Zeller Bernward)"

Sökning: hsv:(MEDICIN OCH HÄLSOVETENSKAP) hsv:(Klinisk medicin) hsv:(Pediatrik) > Zeller Bernward

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Numrering	Referens	Omslagsbild	Hitta
1.	Hasle, Henrik, et al. (författare) Gemtuzumab ozagamicin is well tolerated as post-consolidation therapy in childhood AML 2008 Ingår i: British Journal of Haematology. ; 141:s1 Konferensbidrag (refereegranskat)
2.	Adolfsen Løhmann, Ditte, et al. (författare) Obesity Is Associated with Favorable Cytogenetic Abnormalities in Pediatric Acute Myeloid Leukemia 2017 Ingår i: Blood. 130 (Supplement 1), 1302.. - 0006-4971 .- 1528-0020. Konferensbidrag (refereegranskat)
3.	Bager, Ninna, et al. (författare) Complex and monosomal karyotype are distinct cytogenetic entities with an adverse prognostic impact in paediatric acute myeloid leukaemia : A NOPHO-DBH-AML study 2018 Ingår i: British Journal of Haematology. - : Wiley. - 0007-1048 .- 1365-2141. ; 183:4, s. 618-628 Tidskriftsartikel (refereegranskat)abstract Data on occurrence, genetic characteristics and prognostic impact of complex and monosomal karyotype (CK/MK) in children with acute myeloid leukaemia (AML) are scarce. We studied CK and MK in a large unselected cohort of childhood AML patients diagnosed and treated according to Nordic Society for Paediatric Haematology and Oncology (NOPHO)-AML protocols 1993-2015. In total, 800 patients with de novo AML were included. CK was found in 122 (15%) and MK in 41 (5%) patients. CK and MK patients were young (median age 2.1 and 3.3 years, respectively) and frequently had FAB M7 morphology (24% and 22%, respectively). Refractory disease was more common in MK patients (15% vs. 4%) and stem cell transplantation in first complete remission was more frequent (32% vs. 19%) compared with non-CK/non-MK patients. CK showed no association with refractory disease but was an independent predictor of an inferior event-free survival (EFS; hazard ratio [HR] 1.43, P = 0.03) and overall survival (OS; HR 1.48, P = 0.01). MK was associated with a poor EFS (HR 1.57, P = 0.03) but did not show an inferior OS compared to non-MK patients (HR 1.14, P = 0.62). In a large paediatric cohort, we characterized AML with non-recurrent abnormal karyotype and unravelled the adverse impact of CK and MK on prognosis.
4.	Bager, Ninna, et al. (författare) Monosomal but not complex karyotype in pediatric AML associated with refractory disease. A NOPHO-DBH-AML study. 2017 Ingår i: NOPHO Annual Meeting Abstracts, 19-23 May 2017 Stockholm, FP-13. Konferensbidrag (övrigt vetenskapligt/konstnärligt)
5.	Borg Hammer, AS, et al. (författare) Hypodiploidy in childhood acute myeloid leukemia: A retrospective cohort studyby the international BFM study group. 2018 Ingår i: NOPHO annual meeting abstracts. - 0006-4971 .- 1528-0020. Konferensbidrag (övrigt vetenskapligt/konstnärligt)
6.	Hasle, Henrik, et al. (författare) AML in children. Experiences from the NOPHO studies 2006 Ingår i: Annals of Hematology. - 0939-5555 .- 1432-0584. ; 85:s1 Konferensbidrag (refereegranskat)
7.	Lohmann, Ditte J. A., et al. (författare) Effect of age and body weight on toxicity and sur vival in pediatric acute myeloid leukemia : results from NOPHO-AML 2004 2016 Ingår i: Haematologica. - : Ferrata Storti Foundation (Haematologica). - 0390-6078 .- 1592-8721. ; 101:11, s. 1359-1367 Tidskriftsartikel (refereegranskat)abstract Treatment for pediatric acute myeloid leukemia is very toxic and the association between outcome and age and Body Mass Index is unclear. We investigated effect of age and Body Mass Index on toxicity and survival in pediatric acute myeloid leukemia. We studied all patients who completed first induction course of NOPHO-AML 2004 (n= 318). Toxicity following induction and consolidation courses (n= 6) was analyzed. The probabilities of toxicity and death were determined using time-to-event analyses with Cox multivariate proportional hazard regression for comparative analyses. Age 10-17 years was associated with sepsis with hypotension [hazard ratio 2.3 (95% confidence interval 1.1-4.6)]. Being overweight (> 1 standard deviation) was associated with requiring supplemental oxygen [1.9 (1.0-3.5)]. The 5-year event-free and overall survival were 47% and 71%. Children aged 10-17 years showed a trend for inferior 5-year overall survival compared to children aged 29 (64% vs. 76%; P= 0.07). Infants showed a trend for superior 5-year event-free survival (66% vs. 43%; P= 0.06). Overweight children aged 10-17 years showed a trend for superior survival [5-year event-free survival 59% vs. 40% (P= 0.09) and 5-year overall survival 78% vs. 56% (P= 0.06)] compared to healthy weight children aged 10-17 years. In conclusion, children aged 10-17 years and overweight children had a higher risk of grade 3-4 toxicity. Children aged 10-17 years showed inferior survival, but, unexpectedly, in this age group overweight children tended to have increased survival. This suggests different pharmacokinetics of chemotherapeutic drugs in adolescents and warrants further studies.
8.	Ommen, HB, et al. (författare) Serial Minimal Residual Disease Assessment by qPCR in Peripheral Blood is an Informative Disease Surveillance Tool in Childhood Acute Myeloid Leukaemia 2018 Ingår i: NOPHO 36th Annual meeting 2018 1 - 5 June, Vilnius, Lithuania. Konferensbidrag (övrigt vetenskapligt/konstnärligt)
9.	Palle, Josefine, et al. (författare) A signature of DNA hypomethylation confers increased risk of relapse and in vitro drug resistance in t(8;21)RUNX1/RUNX1T1 pediatric AML 2017 Ingår i: NOPHO Annual Meeting Abstracts, 19-23 May 2017 Stockholm, PO-51. Konferensbidrag (övrigt vetenskapligt/konstnärligt)
10.	Wendtland Edslev, Pernille, et al. (författare) Age and Prognosis in Pediatric AML 2008 Ingår i: Blood. - 1528-0020 .- 0006-4971. ; 112:11 Konferensbidrag (refereegranskat)

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Typ av publikation: tidskriftsartikel (20); konferensbidrag (14)

Typ av innehåll: refereegranskat (26); övrigt vetenskapligt/konstnärligt (8)

Författare/redaktör: Zeller, Bernward (34)Ta bort avgränsningen; Hasle, Henrik (32); Abrahamsson, Jonas, ... (24); Lausen, Birgitte (22); Jahnukainen, Kirsi (22); Forestier, Erik (18); visa fler...; Jonsson, Olafur G. (17); Palle, Josefine (16); Ha, Shau-Yin (14); Heldrup, Jesper (13); Abrahamsson, Jonas (10); Gustafsson, Göran (7); Palle, Josefine, 196 ... (7); Kjeldsen, Eigil (7); Hovi, Liisa (6); Jonmundsson, Gudmund ... (6); Koskenvuo, Minna (6); De Moerloose, Barbar ... (6); Clausen, Niels (5); Asdahl, Peter H. (3); Jonsson, OG (3); Palmqvist, Lars, 196 ... (3); Hovland, Randi (3); Kaspers, Gertjan J. ... (2); Kaspers, GJ (2); Rosenquist, Richard (2); Kanduri, Meena, 1974 (2); Schmiegelow, Kjeld (2); Taskinen, Mervi (2); Ehrencrona, Hans (2); Harila-Saari, Arja (1); Larsson, Rolf (1); Abildgaard, Lotte (1); Ellebaek, Eva (1); Ha, SY (1); Adolfsen Løhmann, Di ... (1); Sung, Lilian (1); Holmberg, Erik, 1951 (1); Juliusson, Gunnar (1); Kovacs, Gabor (1); Walter, C (1); Fogelstrand, Linda, ... (1); Nordlund, Jessica (1); Haltrich, I (1); Kovacs, G (1); Heyman, Mats (1); Harrison, C (1); Jonsson, Olafur Gisl ... (1); Vaitkeviciene, Goda (1); Karlsson, Lene (1); visa färre...

Lärosäte: Göteborgs universitet (24); Uppsala universitet (15); Umeå universitet (13); Lunds universitet (8); Karolinska Institutet (8)

Språk: Engelska (34)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (34)

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