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Doyle, Scott, et al.
(författare)
Evaluation of effects of JPEG2000 compression on a computer-aided detection system for prostate cancer on digitized histopathology
2010
Ingår i: Biomedical Imaging. ; , s. 1313-1316
Konferensbidrag (refereegranskat) abstract
A single digital pathology image can occupy over 10 gigabytes of hard disk space, rendering it difficult to store, analyze, and transmit. Though image compression provides a means of reducing the storage requirement, its effects on computer-aided diagnosis (CAD) and pathologist performance are not yet clear. In this work we assess the impact of compression on the ability of a CAD system to detect carcinoma of the prostate (CaP) on histological sections. The CAD algorithm proceeds as follows: Glands in the tissue are segmented using a region-growing algorithm, and the size of each gland is extracted. A Markov prior (specifically, a probabilistic pairwise Markov model) is employed to encourage nearby glands to share the same class (i.e. cancerous or non-cancerous). Finally, cancerous glands are aggregated into continuous regions using a distancehull algorithm. We trained the CAD system on 28 images of wholemount histology (WMH) and evaluated performance on 12 images compressed at 14 different compression ratios (a total of 168 experiments) using JPEG2000. Algorithm performance (measured using the under the receiver operating characteristic curves) remains relatively constant for compression ratios up to1 :256, beyond which performance degrades precipitously. For completeness we also have an expert pathologist view a randomly-selected set of compressed images from one of the whole mount studies and assign a confidence measure as to their diagnostic fidelity. Pathologist confidence declined with increasing compression ratio as the information necessary to diagnose the sample was lost, dropping from 100% confidence at ratio 1:64 to 0% at ratio 1:8192.
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Hadwiger, Markus, et al.
(författare)
Advanced Illumination Techniques for GPU-Based Volume Raycasting
2009
Annan publikation (övrigt vetenskapligt/konstnärligt) abstract
Volume raycasting techniques are important for both visual arts and visualization. They allow an efficient generation of visual effects and the visualization of scientific data obtained by tomography or numerical simulation. Thanks to their flexibility, experts agree that GPU-based raycasting is the state-of-the art technique for interactive volume rendering. It will most likely replace existing slice-based techniques in the near future. Volume rendering techniques are also effective for the direct rendering of implicit surfaces used for soft body animation and constructive solid geometry.The lecture starts off with an in-depth introduction to the concepts behind GPU-based ray-casting to provide a common base for the following parts. The focus of this course is on advanced illumination techniques which approximate the physically-based light transport more convincingly. Such techniques include interactive implementation of soft and hard shadows, ambient occlusion and simple Monte-Carlo based approaches to global illumination including translucency and scattering. With the proposed techniques, users are able to interactively create convincing images from volumetric data whose visual quality goes far beyond traditional approaches. The optical properties in participating media are defined using the phase function. Many approximations to the physically based light transport applied for rendering natural phenomena such as clouds or smoke assume a rather homogenous phase function model. For rendering volumetric scans on the other hand different phase function models are required to account for both surface-like structures and fuzzy boundaries in the data. Using volume rendering techniques, artists who create medical visualization for science magazines may now work on tomographic scans directly, without the necessity to fall back to creating polygonal models of anatomical structures.
4.
Hadwiger, Markus, et al.
(författare)
Advanced illumination techniques for GPU volume raycasting
2008
Ingår i: ACM Siggraph Asia 2008 Courses. ; , s. 1-11
Konferensbidrag (refereegranskat) abstract
Volume raycasting techniques are important for both visual arts and visualization. They allow an efficient generation of visual effects and the visualization of scientific data obtained by tomography or numerical simulation. Thanks to their flexibility, experts agree that GPU-based raycasting is the state-of-the art technique for interactive volume rendering. It will most likely replace existing slice-based techniques in the near future. Volume rendering techniques are also effective for the direct rendering of implicit surfaces used for soft body animation and constructive solid geometry.The lecture starts off with an in-depth introduction to the concepts behind GPU-based ray-casting to provide a common base for the following parts. The focus of this course is on advanced illumination techniques which approximate the physically-based light transport more convincingly. Such techniques include interactive implementation of soft and hard shadows, ambient occlusion and simple Monte-Carlo based approaches to global illumination including translucency and scattering. With the proposed techniques, users are able to interactively create convincing images from volumetric data whose visual quality goes far beyond traditional approaches. The optical properties in participating media are defined using the phase function. Many approximations to the physically based light transport applied for rendering natural phenomena such as clouds or smoke assume a rather homogenous phase function model. For rendering volumetric scans on the other hand different phase function models are required to account for both surface-like structures and fuzzy boundaries in the data. Using volume rendering techniques, artists who create medical visualization for science magazines may now work on tomographic scans directly, without the necessity to fall back to creating polygonal models of anatomical structures.
5.
Hernell, Frida, et al.
(författare)
Local Ambient Occlusion in Direct Volume Rendering
2010
Ingår i: IEEE Transactions on Visualization and Computer Graphics. - : IEEE. - 1077-2626 .- 1941-0506. ; 16:4, s. 548-559
Tidskriftsartikel (refereegranskat) abstract
This paper presents a novel technique to efficiently compute illumination for Direct Volume Rendering using a local approximation of ambient occlusion to integrate the intensity of incident light for each voxel. An advantage with this local approach is that fully shadowed regions are avoided, a desirable feature in many applications of volume rendering such as medical visualization. Additional transfer function interactions are also presented, for instance, to highlight specific structures with luminous tissue effects and create an improved context for semitransparent tissues with a separate absorption control for the illumination settings. Multiresolution volume management and GPU-based computation are used to accelerate the calculations and support large data sets. The scheme yields interactive frame rates with an adaptive sampling approach for incrementally refined illumination under arbitrary transfer function changes. The illumination effects can give a better understanding of the shape and density of tissues and so has the potential to increase the diagnostic value of medical volume rendering. Since the proposed method is gradient-free, it is especially beneficial at the borders of clip planes, where gradients are undefined, and for noisy data sets.
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