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Sökning: hsv:(SAMHÄLLSVETENSKAP) hsv:(Juridik) > Karolinska Institutet > Medicin och hälsovetenskap

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1.
  • Binde, Per, 1956, et al. (författare)
  • Criminogenic problem gambling: A study of verdicts by Swedish courts
  • 2021
  • Ingår i: International Gambling Studies. - : Informa UK Limited. - 1445-9795 .- 1479-4276. ; 22:3, s. 344-364
  • Tidskriftsartikel (refereegranskat)abstract
    • This study explored the characteristics and consequences of criminogenic problem gambling in Sweden. All verdicts (N = 283,884) delivered by Swedish general courts between 2014 and 2018 were subjected to a key word search for the term ‘problem gambling’ and its synonyms. Verdicts that met the search criterion (n = 1,232) were inspected manually and cases in which problem gambling clearly was the main cause for committing crime (n = 282) were analyzed quantitatively. The most common types of crimes were fraud and embezzlement (67%). Each year around 400 individuals, companies, and organizations became victims of gambling-driven crimes, with nonprofit organizations being the most severely affected. Those convicted for such crimes were older, and to a greater extent female and first-time offenders, compared to national statistics on crimes in general. This suggests that in Sweden, middle-aged women are a high-risk group for severe gambling problems that should be monitored particularly closely by gambling companies for indications of problematic gambling. We conclude that although crimes driven by problem gambling are relatively rare in the justice system, they bring considerable harm to victims and the perpetrators themselves.
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  • Lynoe, Niels, et al. (författare)
  • Police in an intensive care unit : what can happen?
  • 2013
  • Ingår i: Journal of Medical Ethics. - : BMJ. - 0306-6800 .- 1473-4257. ; 39:12, s. 772-775
  • Tidskriftsartikel (refereegranskat)abstract
    • During spring 2009 a Swedish senior paediatric intensivist and associate professor was detained and later prosecuted for mercy-killing a child with severe brain damage. The intensivist was accused of having used high doses of thiopental after having withdrawn life-sustaining treatment when the child was imminently dying. After more than 2.5years of investigation the physician was acquitted by the Stockholm City Court. The court additionally stated that the physician had provided good end-of-life care. Since the trial it has become evident that the accusation was based on a problematic medicolegal report. Nevertheless, the event has had severe negative consequences for the physician personally and professionally, and probably also, in general, for patients in the final stage of life. This case illustrates, together with other cases, that there is a lack of correspondence between ethical soft law/healthcare law and the Penal Code. To optimise medical practice we suggest that the criminal law be carefully examined and if possible changed. Furthermore, we suggest a peer-review system for assessing medicolegal reports in cases of suspected homicide.
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4.
  • Åström, Therese, et al. (författare)
  • Treatment Foster Care Oregon for Delinquent Adolescents: A Systematic Review and Meta-Analysis
  • 2020
  • Ingår i: Research on social work practice. - : SAGE Publications. - 1049-7315 .- 1552-7581. ; 30:4, s. 355-367
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose To examine the effects of Treatment Foster Care on youth with serious behavior problems. Method Included studies are controlled trials with high or medium quality, published between 1990 and September 2017. The control group consists of youth with serious behavior problems in group care, and the follow-up time was at least 12 months. The review also examines ethical and economic aspects. Results A total of eight controlled studies were included, consisting of 633 young people and 55 effect sizes. All studies examined the same model, Treatment Foster Care Oregon (TFCO). There is moderate certainty of evidence that TFCO reduces the risk of future criminal behavior and the number of days in locked settings. Furthermore, there is low certainty of evidence that TFCO reduces the risk of delinquent peer associations, drug use, and depression. Discussion TFCO is to be preferred to group care for youth with serious behavior problems. Ethical and economic implications are discussed.
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5.
  • Bamvita, Jean-Marie, et al. (författare)
  • Childhood predictors of adult psychopathy scores among males followed from age 6 to 33
  • 2017
  • Ingår i: Journal of criminal justice. - : Elsevier BV. - 0047-2352 .- 1873-6203. ; 53, s. 55-65
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: Psychopathic traits are associated with multiple negative outcomes. The present prospective, longitudinal study identified associations of childhood factors with adult psychopathy scores.Methods: 311 men, aged, on average, 33 years, were assessed using the Psychopathy Checklist-Revised (PCL-R). Predictors included neighbourhood deprivation, parents' characteristics, teacher ratings of behaviour at ages 6, 10 and 12, and academic performance at age 12. Hierarchical linear regression models were computed to identify predictors at different ages of PCL-R total and facet scores.Results: Age 33 PCL-R total and facet scores were significantly, and independently, associated with father's and mother's criminality and mother's age at participant's birth when teacher ratings of childhood behaviours and mathematics marks were included in the models. Anxiety was negatively associated with facet 1 scores at age 6. At age 12, 22% of the variance in facet 2 scores was predicted by father's violent convictions, mother's age and criminal charges, and reactive aggression. Facet 3 scores were associated with mother's age (marginally), inattention, and reactive aggression. Facet 4 scores were associated with father's violent criminality, mother's age, conduct probleins, inattention, and reactive aggression.Conclusion: Etiological research and prevention programs should focus on antecedents of psychopathic traits present in early childhood.
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6.
  • Hallinan, D., et al. (författare)
  • International transfers of personal data for health research following Schrems II: a problem in need of a solution
  • 2021
  • Ingår i: European Journal of Human Genetics. - : Springer Science and Business Media LLC. - 1018-4813 .- 1476-5438. ; 29, s. 1502-1509
  • Tidskriftsartikel (refereegranskat)abstract
    • On 16 July 2020, the Court of Justice of the European Union issued their decision in the Schrems II case concerning Facebook’s transfers of personal data from the EU to the US. The decision may have significant effects on the legitimate transfer of personal data for health research purposes from the EU. This article aims: (i) to outline the consequences of the Schrems II decision for the sharing of personal data for health research between the EU and third countries, particularly in the context of the COVID-19 pandemic; and, (ii) to consider certain options available to address the consequences of the decision and to facilitate international data exchange for health research moving forward. © 2021, The Author(s).
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  • Siponen, Rebecca, 1993-, et al. (författare)
  • Psychiatric diagnoses and criminal convictions in youth : A population-based study of comorbidities of diagnoses
  • 2023
  • Ingår i: Journal of criminal justice. - : Elsevier. - 0047-2352 .- 1873-6203. ; 88
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Psychiatric diagnoses are important risk factors for criminal convictions, but few longitudinal studies have examined comorbidity patterns in relation to youth criminal convictions.Aim: To explore associations between specific psychiatric diagnoses (substance use disorder (SUD), ADHD, depression, PTSD, intellectual disabilities (ID), and autism spectrum disorders (ASD)) and comorbidities of internalizing, externalizing, or neurodevelopmental diagnoses (NDD) in relation to risk of non-violent or violent criminal convictions in youth, including potential sex differences.Methods: Data on 1,411,538 individuals born in Sweden (1985–1998) were obtained from national population-based registers. Exposure was psychiatric diagnoses and outcome was criminal convictions between ages 15 and 20.Results: 17% of individuals had a psychiatric diagnosis, of whom 20% were convicted of a crime. All diagnoses, except ID and ASD, increased the risk of non-violent and violent crimes. Comorbidities of externalizing and internalizing diagnoses heightened the risk compared to single diagnoses. NDD increased the risk among SUD, depression, and PTSD, while NDD comorbid with another NDD decreased the risk for criminal convictions.Conclusion: Of the three comorbidity categories, externalizing disorders heightened risk the most, followed by internalizing disorders. This study highlights specific risk patterns for criminal convictions related to comorbidities, and to crime type and sex.
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9.
  • Llona-Minguez, S, et al. (författare)
  • Small-molecule inhibitors of IκB kinase (IKK) and IKK-related kinases
  • 2013
  • Ingår i: Pharmaceutical patent analyst. - : Future Science Ltd. - 2046-8962 .- 2046-8954. ; 2:4, s. 481-98
  • Tidskriftsartikel (refereegranskat)abstract
    • The transcription factors NF-κB and IFN control important signaling cascades and mediate the expression of a number of important pro-inflammatory cytokines, adhesion molecules, growth factors and anti-apoptotic survival proteins. IκB kinase (IKK) and IKK-related kinases (IKKε and TBK1) are key regulators of these biological pathways and, as such, modulators of these enzymes may be useful in the treatment of inflammatory diseases and cancer. We have reviewed the most recent IKK patent literature (2008–2012), added publications of interest overlooked in previous patent reviews and identified all the players involved in small-molecule inhibitors of the IKKs. This will provide the reader with a decisive summary of the IKK arena, a field that has reached maturity over a decade of research.
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10.
  • Mie, Axel, 1974-, et al. (författare)
  • Non-disclosure of developmental neurotoxicity studies obstructs the safety assessment of pesticides in the European Union
  • 2023
  • Ingår i: Environmental Health. - 1476-069X. ; 22
  • Tidskriftsartikel (refereegranskat)abstract
    • Background In the European Union (EU), the safety assessment of plant protection products relies to a large extent on toxicity studies commissioned by the companies producing them. By law, all performed studies must be included in the dossier submitted to authorities when applying for approval or renewal of the active substance.Methods For one type of toxicity, i.e. developmental neurotoxicity (DNT), we evaluated if studies submitted to the U.S. Environmental Protection Agency (EPA) had also been disclosed to EU authorities.Results We identified 35 DNT studies submitted to the U.S. EPA and with the corresponding EU dossiers available. Of these, 9 DNT studies (26%) were not disclosed by the pesticide company to EU authorities. For 7 of these studies, we have identified an actual or potential regulatory impact.Conclusions We conclude that (1) non-disclosure of DNT studies to EU authorities, in spite of clear legal requirements, seems to be a recurring phenomenon, (2) the non-disclosure may introduce a bias in the regulatory risk assessment, and (3) without full access to all performed toxicity studies, there can be no reliable safety evaluation of pesticides by EU authorities. We suggest that EU authorities should cross-check their data sets with their counterparts in other jurisdictions. In addition, applications for pesticide approval should be cross-checked against lists of studies performed at test facilities operating under Good Laboratory Practice (GLP), to ensure that all studies have been submitted to authorities. Furthermore, rules should be amended so that future studies should be commissioned by authorities rather than companies. This ensures the authorities’ knowledge of existing studies and prevents the economic interest of the company from influencing the design, performance, reporting and dissemination of studies. The rules or practices should also be revised to ensure that non-disclosure of toxicity studies carries a significant legal risk for pesticide companies.
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