| 31. |
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| 32. |
- Gillberg, Christopher, 1950, et al.
(författare)
-
Childhood psychosis and computed tomographic brain scan findings.
- 1983
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Ingår i: Journal of Autism and Developmental Disorders. - 0162-3257. ; 13:1, s. 19-32
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Tidskriftsartikel (refereegranskat)abstract
- Twenty-seven infantile autistic children, nine children with other kinds of childhood psychoses, 23 children with mental retardation, and 16 normal children were examined with computerized tomography of the brain. Gross abnormalities were seen in 26% of the autism cases. It was also estimated that about the same proportion of a total population of infantile autistic children show gross changes of CT brain scan. Abnormalities in the region of the frontal horns of the ventricular system tended to be more common in the psychosis groups than in the normal group. Clear-cut right occipital protuberation was rather common in the small group of other psychoses cases but was only marginally more common in the autism than in the normal group. Evans' ratio was significantly higher in all three abnormal groups than in the normal group.
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| 33. |
- Gillberg, Christopher, 1950, et al.
(författare)
-
Childhood psychosis and monoamine metabolites in spinal fluid.
- 1983
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Ingår i: Journal of Autism and Developmental Disorders. - 0162-3257. ; 13:4, s. 383-396
-
Tidskriftsartikel (refereegranskat)abstract
- Determination of monoamine metabolites was accomplished in the spinal fluid of 22 psychotic children and in 22 sex- and almost-age-matched "normal" controls. Also, specimens from groups of mentally retarded children and children with progressive encephalopathy or meningitis were used for comparison. The psychotic children showed raised levels of homovanillic acid. Thirteen children diagnosed as autistic by Rutter's criteria showed isolated increase of this metabolite. In the group of 9 children with other psychoses, both the level of homovanillic acid and that of 5-hydroxy-indoleacetic acid was raised. The comparison with the group of "simply" mentally retarded children and results within the psychotic group revealed that the increased concentration of monoamines was not attributable to mental retardation per se.
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| 34. |
- Gillberg, Christopher, 1950, et al.
(författare)
-
Childhood psychosis and neurofibromatosis--more than a coincidence?
- 1984
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Ingår i: Journal of Autism and Developmental Disorders. - 0162-3257. ; 14:1, s. 1-8
-
Tidskriftsartikel (refereegranskat)abstract
- Three children with both childhood psychosis and neurofibromatosis are reported from a total population screening of psychotic disorder in childhood that had produced 51 cases born in the years 1962-1976 in the Göteborg region, Sweden. The findings suggest that the simultaneous occurrence of neurofibromatosis and childhood psychosis might be more than a coincidence. Underlying monoaminergic dysfunction is postulated as one possible reason for the finding.
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| 35. |
- Gillberg, Christopher, 1950, et al.
(författare)
-
Childhood psychosis in a case of Moebius syndrome.
- 1984
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Ingår i: Neuropediatrics. - : Georg Thieme Verlag KG. - 0174-304X .- 1439-1899. ; 15:3, s. 147-149
-
Tidskriftsartikel (refereegranskat)abstract
- A case of a five-year-old boy with Moebius syndrome, mild-moderate mental retardation and childhood psychosis (possibly infantile autism) is described. This is probably the first case ever of concomitant Moebius syndrome and childhood psychosis to be reported. Brainstem dysfunction is proposed as a common denominator in the neurologic and psychiatric syndrome.
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| 36. |
- Gillberg, Christopher, 1950, et al.
(författare)
-
Children born to mentally retarded women: a 1-21 year follow-up study of 41 cases.
- 1983
-
Ingår i: Psychological Medicine. - 0033-2917. ; 13:4, s. 891-894
-
Tidskriftsartikel (refereegranskat)abstract
- Fifteen mentally retarded Swedish women, judged to be a representative sample, gave birth to 41 children. These children were followed up at the age of 1-21 years with regard to registrations in the Social Register, the Board for Provisions and Services to the Mentally Retarded and the files of the Child and Youth Psychiatric Departments. One child had died, and of the remaining 40 85% had or had exhibited severe psychosocial problems according to register data. The implications of the findings are discussed.
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| 37. |
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| 38. |
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| 39. |
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| 40. |
- Gillberg, Christopher, 1950, et al.
(författare)
-
Endorphin activity in childhood psychosis. Spinal fluid levels in 24 cases.
- 1985
-
Ingår i: Archives of General Psychiatry. - 0003-990X. ; 42:8, s. 780-783
-
Tidskriftsartikel (refereegranskat)abstract
- Twenty 2- to 13-year-old infantile autistic children (16 boys and four girls) and four 4- to 13-year-old children (two boys and two girls) with other kinds of childhood psychoses were compared with eight 6-month-old to 6-year-old normal children with regard to cerebrospinal fluid contents of endorphin fractions I and II. The psychosis groups showed higher mean cerebrospinal fluid endorphin fraction II levels, and 11 (55%) of the 20 autistic patients showed values higher than the highest in the group of normal children. There was a trend toward a correlation between high fraction II levels and self-destructiveness and decreased pain sensibility in the psychotic children. The results are regarded as preliminary but as warranting further research in this potentially fruitful field.
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