| 1. |
- Thörne, Johan, et al.
(författare)
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Effect of ticlopidine and prostaglandin E on endotoxin-induced pulmonary platelet sequestration in vivo
- 1986
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Ingår i: Circulatory Shock. - 0092-6213. ; 20:1, s. 61-69
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Tidskriftsartikel (refereegranskat)abstract
- Prostaglandin E1 has earlier been shown to decrease pulmonary platelet trapping (PPT) following shock. This experiment was performed to evaluate a new method to study PPT in vivo, and to study the effect of prostaglandin E1 and a new antiplatelet drug (ticlopidine) on PPT in rabbits after i.v. administration of endotoxin. Following platelet labeling with In-111, the rabbits were placed under a scintillation camera for continuous measuring of the activity distribution for 40 minutes. The first five minutes represented reference values, whereafter endotoxin E. coli was injected i.v. The following 2-4 minutes showed a sudden increase of radioactivity over the lungs and a simultaneous decrease over the heart, indicating PPT in the nontreated animals, followed by a slow decrease to almost preshock values during the following 30 minutes. Animals receiving prostaglandin E1 showed a significantly lower activity peak in the lungs after the administration of endotoxin, while the corresponding peak in ticlopidine-treated animals did not differ from that seen in the nontreated animals. In all groups, endotoxin caused a decrease in platelet count, but it was significantly lower in the PGE1-treated animals. The results have shown that this diagnostic model for PPT is reliable and may be used for evaluation of the effect on platelet aggregation in vivo of different drugs
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| 2. |
- Bengnér, Urban, et al.
(författare)
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Epidemiology of ankle fracture 1950 and 1980. Increasing incidence in elderly women
- 1986
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Ingår i: Acta Orthopaedica Scandinavica. - : Medical Journals Sweden AB. - 0001-6470. ; 57:1, s. 35-37
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Tidskriftsartikel (refereegranskat)abstract
- During 1980-82, 739 ankle fractures occurred in Malmo. These were compared with 383 ankle fractures occurring in 1950-52. In men there was an increase in the age-specific incidence up to the age of 60, especially in fractures of the lateral malleolus. In women there was an increase in the age-specific incidence above the age of 50, both in lateral malleolar fractures and, even more pronounced, in bi- and tri- malleolar fractures.
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| 3. |
- Bengnér, Urban, et al.
(författare)
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Increasing incidence of tibia condyle and patella fractures
- 1986
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Ingår i: Acta Orthopaedica Scandinavica. - : Medical Journals Sweden AB. - 0001-6470. ; 57:4, s. 334-336
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Tidskriftsartikel (refereegranskat)abstract
- The age and sex specific incidence of tibial condyle fractures and patellar fractures were compared between 1950-55 and 1980-83 in the urban population of Malmo. In elderly women there was an increased incidence over these 30 years for both fracture types.
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| 5. |
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| 6. |
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| 7. |
- Knöös, Tommy, et al.
(författare)
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A method for conversion of hounsfield number to electron density and prediction of macroscopic pair production cross-sections
- 1986
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Ingår i: Radiotherapy and Oncology. - 1879-0887. ; 5:4, s. 337-345
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Tidskriftsartikel (refereegranskat)abstract
- A method for the determination of electron density using a narrow beam attenuation geometry is described. The method does not require that the elemental composition of the phantom materials is known. The Hounsfield numbers for the phantom materials used were determined using five different CT scanners. A relationship between Hounsfield number and electron density can thus be established, which is of considerable value in radiation therapy treatment planning procedures. Measurements of the ratio coherent/incoherent scattering of low energy photons in a certain geometry has proven valuable for determination of atomic number, which in its turn can be used for estimation of macroscopic pair production coefficients for high energy photons. The combination of knowledge of electron density with methods for determination of processes, dependent on atomic number, can form a base for adequate composition of phantom materials for purposes of testing dose calculation algorithms for photons and electrons.
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| 8. |
- Knöös, Tommy, et al.
(författare)
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Comparison of measured and calculated absorbed doses from tangential irradiation of the breast
- 1986
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Ingår i: Radiotherapy and Oncology. - 1879-0887. ; 7:1, s. 81-88
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Tidskriftsartikel (refereegranskat)abstract
- Calculated absorbed dose distributions from tangential irradiation of the breast have been compared with TLD measurements in a anthropomorfic body-shaped phantom which has gone through all phases of the radiation treatment planning cycle, including mapping of electron densities with a CT scanner, simulation of beam set-up and several treatments with an accelerator. The absorbed doses, measured in the breast are 2-6% lower than those calculated with the clinically used treatment planning system. The deviation is slightly higher when wedges are used. The main source for this deviation is shown to be the limitations in the loss-of-scatter correction in the dose calculation algorithm used. It has also been noted that the variation of the absorbed dose in the target volume is in general smaller than predicted by the calculations.
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