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Global cell sorting...
Global cell sorting in the C. elegans embryo defines a new mechanism for pattern formation
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Schnabel, R. (författare)
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Bischoff, M. (författare)
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- Hintze, Arend, Professor (författare)
- Technische Universität Braunschweig Carolo Wilhelmina, Institut für Genetik, Braunschweig, Germany
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Schulz, A. -K (författare)
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Hejnol, A. (författare)
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Meinhardt, H. (författare)
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Hutter, H. (författare)
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(creator_code:org_t)
- Academic Press Inc. 2006
- 2006
- Engelska.
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Ingår i: Developmental Biology. - : Academic Press Inc.. - 0012-1606 .- 1095-564X. ; 294:2, s. 418-431
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- 4D microscopic observations of Caenorhabditis elegans development show that the nematode uses an unprecedented strategy for development. The embryo achieves pattern formation by sorting cells, through far-ranging movements, into coherent regions before morphogenesis is initiated. This sorting of cells is coupled to their particular fate. If cell identity is altered by experiment, cells are rerouted to positions appropriate to their new fates even across the whole embryo. This cell behavior defines a new mechanism of pattern formation, a mechanism that is also found in other animals. We call this new mechanism "cell focusing". When the fate of cells is changed, they move to new positions which also affect the shape of the body. Thus, this process is also important for morphogenesis. © 2006 Elsevier Inc. All rights reserved.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
Nyckelord
- 4D microscopy
- Bioinformatics
- Cell guidance
- Cell migration
- Pattern formation
- animal cell
- animal tissue
- article
- Caenorhabditis elegans
- cell fate
- cell function
- cell maturation
- cell selection
- embryo
- morphogenesis
- nematode
- nonhuman
- priority journal
- Animalia
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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