Salivary microbial profiles in 5-year old children with oral clefts : a comparative study

• Aim: To compare the salivary microbial profile in children with oral clefts to matched non-cleft controls in a cross-sectional study.Methods: The cleft group consisted of 80 children aged 5 years and 144 age-matched non-cleft children were recruited as a control group. Stimulated whole saliva samples were collected and analysed with checkerboard DNA–DNA hybridisation using 12 pre-determined bacterial probes. Background data on caries, oral hygiene, dietary habits and fluoride exposure were collected from clinical examinations and questionnaires.Results: Children in the cleft group had a significantly higher prevalence of dental caries but only minor differences in the salivary microbial profile were found. In general, the cleft-children displayed a lower prevalence of common commensal species (e.g. Streptococcus, Fusobacterium) when compared with the non-cleft controls. The differences were statistically significant (p < 0.05) but the clinical significance was unclear.Conclusions: The profile of the salivary microflora in 5-year-old children with and without oral clefts was basically similar and displayed only marginal differences with respect to commensal bacteria. 

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Odontologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dentistry (hsv//eng)

Nyckelord

Caries

Children

Cleft lip and palate

Oral hygiene

Salivary microflora

cleft lip

cleft palate

comparative study

complication

cross-sectional study

dental caries

female

human

male

microbiology

preschool child

prevalence

questionnaire

saliva

Child

Preschool

Cross-Sectional Studies

Humans

Surveys and Questionnaires

Salivary microflora

Caries

Oral hygiene

Cleft lip and palate

Children

lip and/or palate

dna-dna hybridization

dental-caries

bacteria

health

adolescents

prevalence

parameters

Dentistry

Oral Surgery & Medicine

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)