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Efficacy of Quinapy...
Efficacy of Quinapyramine Sulphate, Isometamedium Chloride and Diminazene Aceturate For Treatment of Surra
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- Amjad, M. (författare)
- University of Veterinary and Animal Sciences, Lahore, Pakistan
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- Saleem, M. H. (författare)
- University of Veterinary and Animal Sciences, Lahore, Pakistan
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- Iqbal, M. Z. (författare)
- University of Veterinary and Animal Sciences, Lahore, Pakistan
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- Hassan, A. (författare)
- Department of Veterinary Surgery and Pet Sciences, Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore, Pakistan
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- Jabbar, A. (författare)
- University of Veterinary and Animal Sciences, Lahore, Pakistan
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- Ashraf, M. (författare)
- University of Veterinary and Animal Sciences, Lahore, Pakistan
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- Qasim, Muhammad (författare)
- Jönköping University,IHH, Statistik
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- Ullah, A. (författare)
- University of Veterinary and Animal Sciences, Lahore, Pakistan
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- Tolba, M. M. (författare)
- Biomedical Informatics and Biotechnology Group, Informatics and Systems Department, Division of Engineering Research, National Research Centre, Cairo, Egypt
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- Nasser, H. A. (författare)
- Microbiology and Public Health Department. Faculty of Pharmacy, Helipolis, University, Egypt
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- Naaz, S. (författare)
- Livestock and Dairy Development Department Punjab Pakistan
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- Ahmad, I. (författare)
- Department of Veterinary Clinical Sciences, University of Poonch Rawalakot Azad Kashmir, Pakistan
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(creator_code:org_t)
- Pakistan Agricultural Scientists Forum, 2022
- 2022
- Engelska.
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Ingår i: Journal of Animal and Plant Sciences. - : Pakistan Agricultural Scientists Forum. - 1018-7081. ; 32:3, s. 663-669
- Relaterad länk:
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https://doi.org/10.3...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- Trypanosomiasis (Surra) is a parasitic and zoonotic disease caused by Trypanosoama evansi, transmitted by insect vectors Tabanus and Stomoxys mechanically. The aim of the present study was to determine the therapeutic efficacy of various trypanosidal drugs against trypanosomiasis in Thoroughbred horses. Horses having clinical signs of trypanosomiasis were diagnosed through blood smear through a microscope were selected for this study. The infected horses were divided into three experimental groups for therapeutic trials. Animals in group A were treated with a single dose of quinapyramine sulphate @ 3000mg/ml per 50/kg body weight; group B was treated with a single dose of isometamedium chloride Hydrochloride@ 0.5 mg/2.5 ml of 1% solution per 50/kg body weight; group C was treated with a single dose of diminazene aceturate@ 2360 mg/15 ml per 100/kg. Results revealed that significant (P<0.0001) de cline in the values of erythrocyte counts (RBC), hemoglobin concentration (Hb), packed cell volume (PCV), platelets (PLT) and a significant (P<0.0001) increase in white blood cells (WBC), granulocytes, and monocytes in infected horses as compared to healthy ones. Therapeutic trials indicated that quinapyramine sulphate that showed 100% efficacy at 21th days had significantly higher than isometamedium chloride and diminazene aceturate (95.83 and 75% efficacy, respectively). The hematological parameters of recovered horses were significantly restored to normal values on day 21 after treatment. It is concluded that quinapyramine sulphate is the drug of choice against trypanosomiasis in Thoroughbred horses.
Ämnesord
- LANTBRUKSVETENSKAPER -- Veterinärmedicin (hsv//swe)
- AGRICULTURAL SCIENCES -- Veterinary Science (hsv//eng)
Nyckelord
- hematological effect
- therapeutic efficacy
- Thoroughbred horses
- Trypanosidal drugs
- Trypanosomiasis
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Amjad, M.
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Saleem, M. H.
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Iqbal, M. Z.
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Hassan, A.
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Jabbar, A.
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Ashraf, M.
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Qasim, Muhammad
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Ullah, A.
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Tolba, M. M.
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Nasser, H. A.
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Naaz, S.
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Ahmad, I.
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Jönköping University