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Technical Requirements for Na18F PET Bone Imaging of Patients Being Treated Using a Taylor Spatial Frame.

Hatherly, Robert (författare)
Department of Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden
Brolin, Fredrik (författare)
Department of Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden
Oldner, Asa (författare)
Department of Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden
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Sundin, Anders (författare)
Uppsala universitet,Enheten för radiologi,Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden
Lundblad, Henrik (författare)
Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden
Maguire Jr., Gerald Q., Jr (författare)
KTH,Radio Systems Laboratory (RS Lab)
Jonsson, Cathrine (författare)
Department of Medical Physics, Karolinska University Hospital, Stockholm, Sweden
Jacobsson, Hans (författare)
Karolinska Institutet
Noz, Marilyn E. (författare)
New York University, Department of Radiology,Nuclear Medicine
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 (creator_code:org_t)
2014-01-16
2014
Engelska.
Ingår i: Journal of nuclear medicine technology. - : Society of Nuclear Medicine. - 1535-5675 .- 0091-4916.
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Diagnosis of new bone growth in patients with compound tibia fractures or deformities treated using a Taylor spatial frame is difficult with conventional radiography because the frame obstructs the images and creates artifacts. The use of Na(18)F PET studies may help to eliminate this difficulty.METHODS: Patients were positioned on the pallet of a clinical PET/CT scanner and made as comfortable as possible with their legs immobilized. One bed position covering the site of the fracture, including the Taylor spatial frame, was chosen for the study. A topogram was performed, as well as diagnostic and attenuation correction CT. The patients were given 2 MBq of Na(18)F per kilogram of body weight. A 45-min list-mode acquisition was performed starting at the time of injection, followed by a 5-min static acquisition 60 min after injection. The patients were examined 6 wk after the Taylor spatial frame had been applied and again at 3 mo to assess new bone growth.RESULTS: A list-mode reconstruction sequence of 1 × 1,800 and 1 × 2,700 s, as well as the 5-min static scan, allowed visualization of regional bone turnover.CONCLUSION: With Na(18)F PET/CT, it was possible to confirm regional bone turnover as a means of visualizing bone remodeling without the interference of artifacts from the Taylor spatial frame. Furthermore, dynamic list-mode acquisition allowed different sequences to be performed, enabling, for example, visualization of tracer transport from blood to the fracture site.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)

Nyckelord

Na18F
PET/CT
Taylor spatial frame
bone imaging

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ref (ämneskategori)
art (ämneskategori)

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