A facile approach toward multifunctional polyethersulfone membranes via in situ cross-linked copolymerization

• In this study, multifunctional polyethersulfone (PES) membranes are prepared via in situ cross-linked copolymerization coupled with a liquid-liquid phase separation technique. Acrylic acid (AA) and N-vinylpyrrolidone (VP) are copolymerized in PES solution, and the solution is then directly used to prepare PES membranes. The infrared and X-ray photoelectron spectroscopy testing, scanning electron microscopy, and water contact angle measurements confirm the successful modification of pristine PES membrane. Protein adsorption, platelet adhesion, plasma recalcification time, and activated partial thromboplastin time assays convince that the modified PES membranes have a better biocompatibility than pristine PES membrane. In addition, the modified membranes showed good protein antifouling property and significant adsorption property of cationic dye. The loading of Ag nanoparticles into the modified membranes endows the composite membranes with antibacterial activity.

Subject headings

TEKNIK OCH TEKNOLOGIER  -- Kemiteknik -- Polymerteknologi (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Chemical Engineering -- Polymer Technologies (hsv//eng)

Keyword

facile

in situ cross-linked copolymerization

multifunctional

polyethersulfone membrane

Biocompatibility

Composite membranes

Copolymerization

Dyes

Hydrogels

Phase separation

Proteins

Scanning electron microscopy

Silver

X ray photoelectron spectroscopy

Activated partial thromboplastin time

Anti-bacterial activity

Liquid phase separation

Plasma recalcification time

Water contact angle measurement

Membranes

1 vinyl 2 pyrrolidinone

acrylic acid

antifouling agent

nanocomposite

polyacrylic acid

polyethersulfone

povidone

protein

silver nanoparticle

water

adsorption

adult

antibacterial activity

anticoagulation

Article

blood compatibility

chemical parameters

contact angle

controlled study

drug delivery system

drug efficacy

fouling control

human

human cell

hydrophilicity

hydrophobicity

in situ cross linked copolymerization

infrared spectroscopy

liquid liquid phase separation

male

nanopharmaceutics

nonhuman

partial thromboplastin time

polymerization

priority journal

thrombocyte adhesion

time

Publication and Content Type

ref (subject category)

art (subject category)