A regio- and stereodivergent synthesis of vic-amino alcohols

• [GRAPHICS] A regio- and stereodivergent synthesis of vic-amino alcohols starting from vinylepoxides is described. The developed strategy focuses on the propensity of vinylepoxides and vinylaziridines to be ring-opened at the allylic position by suitable nucleophiles and makes use of reactions that perform such tasks selectively with either retention or inversion of configuration.

Ämnesord

NATURVETENSKAP  -- Kemi -- Organisk kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Organic Chemistry (hsv//eng)

Nyckelord

asymmetric-synthesis

1,2-amino alcohols

beta-amino

enantioselective synthesis

opening reaction

building-blocks

aziridines

efficient

rearrangement

epoxides

organisk kemi

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)