Asymmetric reduction of azirines; a new route to chiral aziridines

• The first enantioselective reduction of aromatic 2H-azirines yields aziridines in up to 70% ee, using the aminoalcohol[RuCl2(p-cymene)](2) catalyzed asymmetric transfer hydrogenation reaction.

Ämnesord

NATURVETENSKAP  -- Kemi -- Organisk kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Organic Chemistry (hsv//eng)

Nyckelord

transfer hydrogenation

alkene aziridination

carbonyl-compounds

ketones

catalysts

complexes

ligand

enantioselectivity

mechanism

alcohols

Organic chemistry

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