A High Performance Computing Framework for Finite Element Simulation of Blood Flow in the Left Ventricle of the Human Heart

• We present a high performance computing framework for finite element simulation of blood flow in the left ventricle of the human heart. The mathematical model is described together with the discretization method and the parallel implementation in Unicorn which is part of the open source software framework FEniCS-HPC. We show results based on patient-specific data that capture essential features observed with other computational models and imaging techniques, and thus indicate that our framework possesses the potential to provide relevant clinical information for diagnosis and medical treatment. Several other studies have been conducted to simulate the three dimensional blood flow in the left ventricle of the human heart with prescribed wall movement. Our contribution to the field of cardiac research lies in establishing an open source framework modular both in modelling and numerical algorithms.

Subject headings

NATURVETENSKAP  -- Matematik -- Beräkningsmatematik (hsv//swe)

NATURAL SCIENCES  -- Mathematics -- Computational Mathematics (hsv//eng)

TEKNIK OCH TEKNOLOGIER  -- Maskinteknik -- Strömningsmekanik och akustik (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Mechanical Engineering -- Fluid Mechanics and Acoustics (hsv//eng)

Keyword

Arbitrary Lagrangian–Eulerian method

Blood flow

Finite element method

Left ventricle

Parallel algorithm

Patient-specific heart model

Blood

Computer programming

Diagnosis

Discrete event simulation

Heart

Hemodynamics

Medical imaging

Numerical methods

Open source software

Open systems

Parallel algorithms

Patient treatment

Eulerian method

Finite element simulations

Heart model

High performance computing

Left ventricles

Open source frameworks

Parallel implementations

Publication and Content Type

ref (subject category)

kon (subject category)