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Gaussian process mo...
Gaussian process modeling of macroscopic kinetics : a better-tailored kernel for Monod-type kinetics
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- Colin, Kevin (författare)
- KTH,Reglerteknik,Centre for Advanced BioProduction by Continuous Processing, AdBIOPRO
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- Hjalmarsson, Håkan, 1962- (författare)
- KTH,Reglerteknik,Centre for Advanced BioProduction by Continuous Processing, AdBIOPRO
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- Chotteau, Véronique, Docent, 1963- (författare)
- KTH,Industriell bioteknologi,Centre for Advanced BioProduction by Continuous Processing, AdBIOPRO
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(creator_code:org_t)
- Elsevier BV, 2022
- 2022
- Engelska.
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Ingår i: 10th Vienna International Conference on Mathematical Modelling MATHMOD 2022 Vienna Austria, 27–29 July 2022. - : Elsevier BV. ; , s. 397-402
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Abstract
Ämnesord
Stäng
- In bioprocesses, it is important to model the kinetics of the macroscopic rates of reactions since these are required to catch the dynamical aspects of a process. In [Wang et al. 2020], a modeling method involving Gaussian processes has been developed, using a kernel especially designed for the modeling of Monod-type kinetics (activation, inhibition, double component, neutral effect). However, as will be illustrated in this paper, when the number of training data is limited or the metabolite concentration data do not have large variations (which is generally the case for real-life data), this kernel can yield inaccurate models for the kinetics. In this paper, we develop a new kernel better tailored for the modeling of Monod-type kinetics and we show that it has good modeling performances in the case of a limited number of data. The idea is to use the particular structure of Monod-type functions in the design of the kernel, i.e., we incorporate prior knowledge in the modeling.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Elektroteknik och elektronik -- Reglerteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Electrical Engineering, Electronic Engineering, Information Engineering -- Control Engineering (hsv//eng)
Nyckelord
- Gaussian process
- Nonlinear system identification
- Monod model
- Kinetics
- Macroscopic modeling
- Chemical Engineering
- Kemiteknik
Publikations- och innehållstyp
- ref (ämneskategori)
- kon (ämneskategori)