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Point-of-care isoth...
Point-of-care isothermal nucleic acid amplification platform for COVID-19 diagnostics in resource-limited settings
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- Soares, Ruben R. G. (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Nanobioteknologi
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- Akhtar, Ahmad Saleem (författare)
- KTH,Nanobioteknologi,Science for Life Laboratory, SciLifeLab
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- Pinto, Ines Fernandes (författare)
- KTH,Nanobioteknologi,Science for Life Laboratory, SciLifeLab
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- Lapins, Noa (författare)
- KTH,Nanobioteknologi,Science for Life Laboratory, SciLifeLab
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- Barrett, Donal (författare)
- Science for Life Laboratory, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden
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- Sandh, Gustaf (författare)
- Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
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- Yin, Xiushan (författare)
- Science for Life Laboratory, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden; Applied Biology Laboratory, Shenyang University of Chemical Technology, Shenyang, China; Biotech and Biomedicine Science Co. Ltd, Shenyang, China
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- Pelechano, Vicent (författare)
- Science for Life Laboratory, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden
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- Russom, Aman, Prof. 1976- (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Nanobioteknologi
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(creator_code:org_t)
- Chemical and Biological Microsystems Society, 2021
- 2021
- Engelska.
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Ingår i: Proceedings MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. - : Chemical and Biological Microsystems Society. ; , s. 863-864
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- The demand for scalable, rapid and sensitive COVID-19 diagnostics is particularly pressing at present to help contain the spread of infection and prevent overwhelming the capacity of health systems. While high-income countries have managed to rapidly expand diagnostic capacities, such is not the case in resource-limited settings of low- to medium-income countries. We report the development of an integrated modular centrifugal microfluidic platform costing less than 250 USD to perform loop-mediated isothermal amplification (LAMP) of viral RNA directly from heat-inactivated nasopharyngeal swab samples. The platform was validated with a panel of 131 nasopharyngeal swab samples collected from symptomatic COVID-19 patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
Nyckelord
- Beads
- Coronavirus
- Diagnostics
- Smartphone
Publikations- och innehållstyp
- ref (ämneskategori)
- kon (ämneskategori)
- Av författaren/redakt...
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Soares, Ruben R. ...
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Akhtar, Ahmad Sa ...
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Pinto, Ines Fern ...
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Lapins, Noa
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Barrett, Donal
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Sandh, Gustaf
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visa fler...
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Yin, Xiushan
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Pelechano, Vicen ...
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Russom, Aman, Pr ...
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Infektionsmedici ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Medicinsk biotek ...
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och Medicinsk biotek ...
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- Proceedings Micr ...
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Kungliga Tekniska Högskolan