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Enzyme Modification
Enzyme Modification
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- Biundo, Antonino (författare)
- University of Bari, Department of Biosciences, Biotechnology and Biopharmaceutics, via Orabona, 4, Bari, 70125, Italy, via Orabona, 4; REWOW srl, Via Ciasca 9, Bari, 70124, Italy, Via Ciasca 9
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- Saénz Méndez, Patricia (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Fiber- och polymerteknologi,Karlstads Universitet, Faculty of Health, Science and Technology, Universitetsgatan 2, 65188 Karlstad, Sweden
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- Görbe, Tamas (författare)
- Menten AI, 2225 E Bayshore Road, Suite 200, Palo Alto, CA, 94303, USA
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(creator_code:org_t)
- 2021-04-30
- 2021
- Engelska.
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Ingår i: Biocatalysis for Practitioners. - : Wiley. ; , s. 33-62
- Relaterad länk:
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https://urn.kb.se/re...
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visa fler...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The chapter on protein engineering has introduced and discussed an overview of the available methods for the modification of enzymes. Starting with the classical directed evolution (DE) technique, which has been applied extensively throughout several different biocatalytic processes, the reader moves toward the semi-rational, rational, and de novo design of enzymes. Meanwhile, DE is clearly the current industry-leading technology; depending on the understanding of the particular enzymatic system, and on the available structural information, other techniques such as rational design are also becoming fast and efficient solutions for the development of new catalysts. This success would not be possible without the constant improvements of the computational techniques and the newly developed modeling systems for enzyme engineering.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Industriell bioteknik -- Biokatalys och enzymteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Industrial Biotechnology -- Biocatalysis and Enzyme Technology (hsv//eng)
Nyckelord
- biocatalyst improvement
- de novo design
- directed evolution
- protein engineering
- rational design
Publikations- och innehållstyp
- vet (ämneskategori)
- kap (ämneskategori)
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