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SPECT in the Kleine...
SPECT in the Kleine–Levin syndrome, a possible diagnostic and prognostic aid?
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- Vigren, Patrick (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för neurovetenskap,Hälsouniversitetet,Neurologiska kliniken,Centrum för medicinsk bildvetenskap och visualisering, CMIV
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- Engström, Maria, 1958- (författare)
- Linköpings universitet,Avdelningen för radiologiska vetenskaper,Hälsouniversitetet,Centrum för medicinsk bildvetenskap och visualisering, CMIV
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- Landtblom, Anne-Marie (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för neurovetenskap,Hälsouniversitetet,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Neurologiska kliniken,Medicinska specialistkliniken,Division of Radiological Sciences, Department of Medical and Health Sciences (IMH), Faculty of Health Sciences, Linköping University, Linköping, Sweden
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(creator_code:org_t)
- 2014-09-23
- 2014
- Engelska.
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Ingår i: Frontiers in Neurology. - Switzerland : Frontiers Research Foundation. - 1664-2295. ; 5:178
- Relaterad länk:
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https://www.frontier...
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visa fler...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Introduction: Kleine–Levin syndrome (KLS) is a rare syndrome of periodic hypersomnia and behavioral and cognitive symptoms based on clinical criteria. In the setting of differential diagnosis of hypersomnia disorders, an objective diagnostic aid is desirable. A promising modality is single photon emission computed tomography (SPECT). As intraepisodal investigations are difficult to perform, an interepisodal investigation would be very helpful. Another aim of the study was to correlate SPECT findings to prognosis.Methods and Materials: Twenty-four KLS-patients were categorized as severe or non-severe based on clinical characteristics. The clinical characteristics were analyzed in relation to SPECT-examinations performed between hypersomnia periods (interepisodal) or after remission, as a clinical routine investigation.Results: Forty-eight percent of the KLS-patients have hypoperfusion in the temporal or fronto-temporal regions. In patients that have undergone remission, 56% show that pattern. There were no specific findings related to prognosis.Discussion/Conclusion: SPECT might be a diagnostic aid, in a setting of hypersomnia experience. With a sensitivity of 48%, interepisodal SPECT alone cannot be used for diagnosing KLS.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- single photon emission tomography
- sleep disorders
- brain perfusion
- Kleine–Levin syndrome
- sleep
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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