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Genetical Genomics ...
Genetical Genomics of Tonic Immobility in the Chicken
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- Fogelholm, Jesper (författare)
- Linköpings universitet,Biologi,Tekniska fakulteten
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- Inkabi, Samuel (författare)
- Linköpings universitet,Biologi,Tekniska fakulteten,AVIAN Behav Genom and Physiol Grp
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- Höglund, Andrey (författare)
- Linköpings universitet,Biologi,Tekniska fakulteten
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- Abbey-Lee, Robin (författare)
- Linköpings universitet,Biologi,Tekniska fakulteten
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- Johnsson, Martin (författare)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics,University of Edinburgh,Univ Edinburgh, Scotland; Swedish Univ Agr Sci, Sweden
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- Jensen, Per (författare)
- Linköpings universitet,Biologi,Tekniska fakulteten
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- Henriksen, Rie (författare)
- Linköpings universitet,Biologi,Tekniska fakulteten
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- Wright, Dominic (författare)
- Linköpings universitet,Biologi,Tekniska fakulteten
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(creator_code:org_t)
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- 2019-05-07
- 2019
- Engelska.
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Ingår i: Genes. - : MDPI. - 2073-4425. ; 10:5
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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https://www.mdpi.com...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://res.slu.se/i...
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Abstract
Ämnesord
Stäng
- Identifying the molecular mechanisms of animal behaviour is an enduring goal for researchers. Gaining insight into these mechanisms enables us to gain a greater understanding of behaviour and their genetic control. In this paper, we perform Quantitative Trait Loci (QTL) mapping of tonic immobility behaviour in an advanced intercross line between wild and domestic chickens. Genes located within the QTL interval were further investigated using global expression QTL (eQTL) mapping from hypothalamus tissue, as well as causality analysis. This identified five candidate genes, with the genes PRDX4 and ACOT9 emerging as the best supported candidates. In addition, we also investigated the connection between tonic immobility, meat pH and struggling behaviour, as the two candidate genes PRDX4 and ACOT9 have previously been implicated in controlling muscle pH at slaughter. We did not find any phenotypic correlations between tonic immobility, struggling behaviour and muscle pH in a smaller additional cohort, despite these behaviours being repeatable within-test.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- LANTBRUKSVETENSKAPER -- Bioteknologi med applikationer på växter och djur -- Genetik och förädling inom lantbruksvetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Agricultural Biotechnology -- Genetics and Breeding in Agricultural Sciences (hsv//eng)
- NATURVETENSKAP -- Biologi -- Etologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Behavioural Sciences Biology (hsv//eng)
Nyckelord
- QTL; eQTL; tonic immobility; behaviour; domestication; muscle pH
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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