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Pre-oxygenation usi...
Pre-oxygenation using high-flow nasal oxygen vs. tight facemask during rapid sequence induction
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- Sjöblom, A. (författare)
- Karolinska Institutet
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- Broms, J. (författare)
- Karolinska Institutet
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- Hedberg, M. (författare)
- Karolinska Univ Hosp Solna, Sweden
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- Lodenius, A. (författare)
- Karolinska Institutet
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- Furubacke, A. (författare)
- Region Östergötland
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- Henningsson, R. (författare)
- Karlstad Cent Hosp, Sweden
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- Wiklund, A. (författare)
- Karolinska Institutet
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- Nabecker, S. (författare)
- Univ Bern, Switzerland
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- Theiler, L. (författare)
- Kantonsspital Aarau, Switzerland
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- Fagerlund, M. Jonsson (författare)
- Karolinska Institutet
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(creator_code:org_t)
- 2021-02-18
- 2021
- Engelska.
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Ingår i: Anaesthesia. - : WILEY. - 0003-2409 .- 1365-2044. ; 76:9, s. 1176-1183
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Pre-oxygenation using high-flow nasal oxygen can decrease the risk of desaturation during rapid sequence induction in patients undergoing emergency surgery. Previous studies were single-centre and often in limited settings. This randomised, international, multicentre trial compared high-flow nasal oxygen with standard facemask pre-oxygenation for rapid sequence induction in emergency surgery at all hours of the day and night. A total of 350 adult patients from six centres in Sweden and one in Switzerland undergoing emergency surgery where rapid sequence induction was required were included and randomly allocated to pre-oxygenation with 100% oxygen using high-flow nasal oxygen or a standard tight-fitting facemask. The primary outcome was the number of patients developing oxygen saturations <93% from the start of pre-oxygenation until 1 min after tracheal intubation. Data from 349 of 350 patients who entered the study were analysed (174 in the high-flow nasal oxygen group and 175 in the facemask group). No difference was detected in the number of patients desaturating <93%, five (2.9%) vs. six (3.4%) patients in the high-flow nasal oxygen and facemask group, respectively (p = 0.77). The risk of desaturation was not increased during on-call hours. No difference was seen in end-tidal carbon dioxide levels in the first breath after tracheal intubation or in the number of patients with signs of regurgitation between groups. These results confirm that high-flow nasal oxygen maintains adequate oxygen levels during pre-oxygenation for rapid sequence induction.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Nyckelord
- emergency; intubation; oxygen desaturation; pre‐ oxygenation; rapid sequence induction
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Sjöblom, A.
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Broms, J.
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Hedberg, M.
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Lodenius, A.
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Furubacke, A.
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Henningsson, R.
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visa fler...
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Wiklund, A.
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Nabecker, S.
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Theiler, L.
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Fagerlund, M. Jo ...
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Anestesi och int ...
- Artiklar i publikationen
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Anaesthesia
- Av lärosätet
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Linköpings universitet
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Karolinska Institutet