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Altered probe press...
Altered probe pressure and body position increase diagnostic accuracy for men and women in detecting hepatic steatosis using quantitative ultrasound
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- Byenfeldt, Marie (författare)
- Umeå universitet,Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Dept Radiol Ostersund, Sweden; Umea Univ, Sweden,Institutionen för strålningsvetenskaper,Department of Radiology in Östersund, Östersund, Sweden; Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Center for Medical Image Science and Visualization, Linköping University, Linköping, Sweden
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- Kihlberg, Johan (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Röntgenkliniken i Linköping,Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Center for Medical Image Science and Visualization, Linköping University, Linköping, Sweden; Department of Radiology in Linköping, Linköping, Sweden
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- Nasr, Patrik (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Mag- tarmmedicinska kliniken,Center for Medical Image Science and Visualization, Linköping University, Linköping, Sweden; Division of Diagnostics and Specialist Medicine, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
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- Grönlund, Christer (författare)
- Umeå universitet,Institutionen för strålningsvetenskaper,Umea Univ, Sweden
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- Lindam, Anna, PhD, 1978- (författare)
- Umeå universitet,Allmänmedicin,Umea Univ, Sweden
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- Bartholomä, Wolf (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Röntgenkliniken i Linköping,Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Center for Medical Image Science and Visualization, Linköping University, Linköping, Sweden
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- Lundberg, Peter (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Medicinsk strålningsfysik,Center for Medical Image Science and Visualization, Linköping University, Linköping, Sweden; Department of Radiation Physics, Linköping University, Linköping, Sweden; Department of Medical and Health Science in Linköping University, Linköping, Sweden
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- Ekstedt, Mattias (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Mag- tarmmedicinska kliniken,Center for Medical Image Science and Visualization, Linköping University, Linköping, Sweden; Division of Diagnostics and Specialist Medicine, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
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(creator_code:org_t)
- 2024
- 2024
- Engelska.
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Ingår i: European Radiology. - : SPRINGER. - 0938-7994 .- 1432-1084.
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- ObjectivesTo evaluate the diagnostic performance of ultrasound guided attenuation parameter (UGAP) for evaluating liver fat content with different probe forces and body positions, in relation to sex, and compared with proton density fat fraction (PDFF).MethodsWe prospectively enrolled a metabolic dysfunction-associated steatotic liver disease (MASLD) cohort that underwent UGAP and PDFF in the autumn of 2022. Mean UGAP values were obtained in supine and 30 degrees left decubitus body position with normal 4 N and increased 30 N probe force. The diagnostic performance was evaluated by the area under the receiver operating characteristic curve (AUC).ResultsAmong 60 individuals (mean age 52.9 years, SD 12.9; 30 men), we found the best diagnostic performance with increased probe force in 30 degrees left decubitus position (AUC 0.90; 95% CI 0.82-0.98) with a cut-off of 0.58 dB/cm/MHz. For men, the best performance was in supine (AUC 0.91; 95% CI 0.81-1.00) with a cut-off of 0.60 dB/cm/MHz, and for women, 30 degrees left decubitus position (AUC 0.93; 95% CI 0.83-1.00), with a cut-off 0.56 dB/cm/MHz, and increased 30 N probe force for both genders. No difference was in the mean UGAP value when altering body position. UGAP showed good to excellent intra-reproducibility (Intra-class correlation 0.872; 95% CI 0.794-0.921).ConclusionUGAP provides excellent diagnostic performance to detect liver fat content in metabolic dysfunction-associated steatotic liver diseases, with good to excellent intra-reproducibility. Regardless of sex, the highest diagnostic accuracy is achieved with increased probe force with men in supine and women in 30 degrees left decubitus position, yielding different cut-offs.Clinical relevance statementThe ultrasound method ultrasound-guided attenuation parameter shows excellent diagnostic accuracy and performs with good to excellent reproducibility. There is a possibility to alter body position and increase probe pressure, and different performances for men and women should be considered for the highest accuracy.Key Points center dot There is a possibility to alter body position when performing the ultrasound method ultrasound-guided attenuation parameter.center dot Increase probe pressure for the highest accuracy.center dot Different performances for men and women should be considered.Key Points center dot There is a possibility to alter body position when performing the ultrasound method ultrasound-guided attenuation parameter.center dot Increase probe pressure for the highest accuracy.center dot Different performances for men and women should be considered.Key Points center dot There is a possibility to alter body position when performing the ultrasound method ultrasound-guided attenuation parameter.center dot Increase probe pressure for the highest accuracy.center dot Different performances for men and women should be considered.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- Fatty liver; Ultrasonography; Magnetic resonance imaging; Sex factors; Patient positioning
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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