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Nerve conduction de...
Nerve conduction defects are retarded by tight metabolic control in type I diabetes
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- Hyllienmark, Lars (författare)
- Department of Clinical Neurophysiology, Karolinska Hospital, Stockholm, Sweden
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- Golster, Helena (författare)
- Linköpings universitet,Klinisk Neurofysiologi,Anestesiologi med intensivvård,Hälsouniversitetet
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- Samuelsson, Ulf, 1951- (författare)
- Linköpings universitet,Pediatrik,Hälsouniversitetet
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- Ludvigsson, Johnny, 1943- (författare)
- Linköpings universitet,Pediatrik,Hälsouniversitetet
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(creator_code:org_t)
- 2001
- 2001
- Engelska.
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Ingår i: Muscle and Nerve. - 0148-639X .- 1097-4598. ; 24:2, s. 240-246
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- This follow-up study examines whether the development of nerve dysfunction is retarded by tight metabolic control in patients with type I diabetes mellitus. Seventy-one patients and 115 age-matched healthy control subjects underwent studies of nerve conduction in peroneal and sural nerves. The presence of diabetes was associated with a reduction in peroneal motor nerve conduction velocity (MCV) by 5.9 m/s, sural sensory nerve conduction velocity (SCV) by 3.4 m/s, and sural sensory nerve action potential (SNAP) amplitude by 22%. Dysfunction in peroneal MCV, sural SCV, and sural SNAP were related to long-term poor metabolic control. Eleven of 12 patients with HbA1c <6.5% had normal nerve conduction or abnormality in only one nerve as compared to 2 of 15 patients with HbA1c >8.0%. It is concluded that tight long-term metabolic control (HbA1c <6.5%) can retard nerve dysfunction in patients with type I diabetes mellitus and a mean disease duration of 12 years.
Nyckelord
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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