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Seasonal variation ...
Seasonal variation in the diagnosis of type 1 diabetes in south-east Sweden
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- Samuelsson, Ulf, 1951- (författare)
- Linköpings universitet,Pediatrik,Hälsouniversitetet
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- Carstensen, John, 1953- (författare)
- Linköpings universitet,Avdelningen för hälsa och samhälle,Hälsouniversitetet
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- Löfman, Owe, 1945- (författare)
- Linköpings universitet,Östergötlands Läns Landsting,Folkhälsovetenskapligt centrum,Hälsouniversitetet
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- Nordfeldt, Sam, 1957- (författare)
- Linköpings universitet,Barn- och ungdomspsykiatri,Hälsouniversitetet
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(creator_code:org_t)
- Elsevier BV, 2007
- 2007
- Engelska.
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Ingår i: Diabetes Research and Clinical Practice. - : Elsevier BV. - 0168-8227 .- 1872-8227. ; 76:1, s. 75-81
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- With the aim to survey the seasonal pattern of diagnosis of type 1 diabetes we included all 1903 children <16 years of age and who had been diagnosed with type 1 diabetes between 1977 and 2001 in the south-east of Sweden. To investigate the seasonal pattern a mixture of two cosine functions was included in a logistic regression model.There was a clear seasonal variation over the years (p < 0.001). Children in the oldest age group (11–15 years) showed the most obvious seasonal variation (p < 0.001). Children with a short duration of symptoms had about the same seasonal variation as children with a long duration. Both children with and without an infection 3 months prior to diagnosis showed significant seasonal variation (p < 0.001) although the seasonal pattern differed between the two groups (p < 0.001). As the incidence of diabetes increased during the 25 years the study period was divided into periods of 5 years and it was only during the two last periods that significant seasonal variation occurred.There is a clear seasonal variation in diagnosis of type 1 diagnosis in children and the results suggest that children with a less aggressive disease process at diagnosis were most responsible for this variation. Children with and without prior infection showed a different seasonal pattern.
Nyckelord
- Type 1 diabetes
- seasonality
- pH-value
- infection
- duration of symptoms
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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