Search: id:"swepub:oai:DiVA.org:liu-46369" >
Elevated number of ...
Elevated number of cells secreting transforming growth factor β in Guillain-Barré syndrome
-
- Dahle, Charlotte (author)
- Linköpings universitet,Neurologi,Klinisk immunologi,Hälsouniversitetet
-
- Kvarnström, Maria (author)
- Linköpings universitet,Klinisk immunologi,Hälsouniversitetet
-
- Ekerfelt, Christina (author)
- Linköpings universitet,Klinisk immunologi,Hälsouniversitetet
-
show more...
-
- Samuelsson, Margareta (author)
- Neurology Unit, Örebro University Hospital, Sweden
-
- Ernerudh, Jan (author)
- Linköpings universitet,Neurologi,Klinisk immunologi,Hälsouniversitetet
-
show less...
-
(creator_code:org_t)
- Wiley, 2003
- 2003
- English.
-
In: Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). - : Wiley. - 0903-4641 .- 1600-0463. ; 111:12, s. 1095-1104
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- We used ELISPOT and cell ELISA to study secretion of IL-4, IFN-γ, TGF-β, IL-6, and TNF-α by circulating mononuclear cells during the course of Guillain-Barré syndrome (GBS). Compared to healthy controls, patients with GBS had higher numbers of TGF-β-secreting cells and the number of individuals with myelin-peptide-induced IL-4 and TGF-β secretion was higher in the GBS group. No significant differences were seen concerning the predominantly pro-inflammatory cytokines IFN-γ, IL-6 or TNF-α. Our findings indicate a down-regulatory role for TGF-β and IL-4 in GBS.
Keyword
- Cytokines
- ELISPOT
- Guillain-Barré
- IL-4
- Syndrome
- TGF-ß
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database