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Artificial corneas :
Artificial corneas : a regenerative medicine approach
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- Griffith, May (författare)
- University of Ottawa
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- Jackson, W B (författare)
- University of Ottawa
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- Lagali, Neil (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Oftalmiatrik,Hälsouniversitetet,Ögonkliniken US/LiM,Landstinget i Östergötland
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- Merrett, K (författare)
- University of Ottawa
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- Li, F (författare)
- University of Ottawa
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- Fagerholm, Per (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Oftalmiatrik,Hälsouniversitetet,Ögonkliniken US/LiM
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(creator_code:org_t)
- 2009-01-16
- 2009
- Engelska.
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Ingår i: EYE. - : Springer Science and Business Media LLC. - 0950-222X .- 1476-5454. ; 23:10, s. 1985-1989
- Relaterad länk:
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https://www.nature.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Corneal substitutes are being developed to address the shortage of human donor tissues as well as the current disadvantages in some clinical indications, which include immune rejection. In the past few years, there have been significant developments in bioengineered corneas that are designed to replace part or the full thickness of damaged or diseased corneas that range from keratoprostheses that solely address the replacement of the corneas function, through tissue-engineered hydrogels that permit regeneration of host tissues. We describe examples of corneal substitutes that encourage regeneration of the host tissue. We also contend that it is unlikely that there will be a single "one-size-fits-all corneal substitute for all indications. Instead, there will most likely be a small range of corneal substitutes ranging from prostheses to tissue-engineered matrix substitutes that are tailored to different clusters of clinical indications. The tissue-engineered matrices can either be produced as sterile acellular matrices, or complete with functional cells, ready for implantation.
Nyckelord
- corneal substitutes
- transplantation
- regeneration
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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