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SALIVARY ALPHA-AMYL...
SALIVARY ALPHA-AMYLASE IN A POPULATION BASED SAMPLE. ASSOCIATIONS WITH PSYCHOSOCIAL FACTORS, SELF RATED HEALTH AND INFLAMMATORY MARKERS
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- Garvin, Peter (författare)
- Linköpings universitet,Socialmedicin och folkhälsovetenskap,Hälsouniversitetet
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- Suska, Anke (författare)
- Linköpings universitet,Tillämpad Fysik,Tekniska högskolan
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- Kristenson, Margareta (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Socialmedicin och folkhälsovetenskap,Hälsouniversitetet,Folkhälsovetenskapligt centrum
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- Lundström, Ingemar (författare)
- Linköpings universitet,Tillämpad Fysik,Tekniska högskolan
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- Ernerudh, Jan (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Klinisk immunologi,Hälsouniversitetet,Klinisk immunologi och transfusionsmedicin
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(creator_code:org_t)
- 2010-07-15
- 2010
- Engelska.
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Ingår i: International Journal of Behavioral Medicine. - : Springer-Verlag New York. - 1070-5503 .- 1532-7558. ; 17:1 Supplement, s. S181-S181
- Relaterad länk:
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https://link.springe...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Objective: In recent years, salivary alpha-amylase (sAA) has beenproposed as a reliable proxy for sympathetic activity. This study aimed at testing the association between sAA to a broad range of psychosocial factors, self rated health, cardiovascular risk factors and inflammatory markers in a normal population sample.Methods: 30 participants, all men between 50 and 54 years old, were randomly selected from a normal population based study. Saliva samples were collected at awakening, 30 minutes after awakening and just before going to bed. sAA was measured by a calorimetric method using Phadebas amylase test. Linear regression models were used to test associations between sAA levels and a broad spectrum of psychosocial factors (e.g. depressive symptamology, vital exhaustion, mastery and sense of coherence) self rated health and inflammatory markers (e.g. C-reactive protein). Adjustments were made for physical exercise, smoking, blood lipids and time point when sample was collected.Results: sAA levels at awakening were positively associated with depressive symptamology (p = 0.046), vital exhaustion (p = 0.025) and negatively associated with sense of coherence (p = 0.034). It was further associated positively associated with levels of C-reactive protein (p = 0.024) and negatively associated with self reported general health (p = 0.010). Samples taken just before going to bed were showing similar results, whereas samples taken 30 minutes after awakening only showed a few significant associations.Conclusions: The associations found give further support for the use of salivary alpha amylase as a psychoneuroendocrinological bio- marker. Assessment just after awakening or just before going to bed seems to be more reliable than samples 30 minutes after awakening.
Nyckelord
- MEDICINE
- MEDICIN
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- art (ämneskategori)
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