POLYFERROCENES AS MEDIATORS IN AMPEROMETRIC BIOSENSORS FOR GLUCOSE

• This paper describes the first successful application of polymeric ferrocenes as mediators in amperometric biosensors. The results have implications for the design of stable biosensors and bioelectronic devices involving electron transfer from oxidoreductases to electrode surfaces. The behaviour of two ferrocene polymers in enzyme electrodes was explored and a distinctive pH profile was noted. It is suggested that changes in either the enzyme conformation or the polymer in response to hydrogen ion concentration may explain the difference in behaviour between monomeric and polymeric ferrocenes.

Nyckelord

AMPEROMETRY; BIOSENSORS; ENZYMATIC METHODS; ENZYME ELECTRODES; FERROCENES; GLUCOSE; GLUCOSE OXIDASE

TECHNOLOGY

TEKNIKVETENSKAP

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