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Sökning: id:"swepub:oai:DiVA.org:liu-81355" > Laser-induced fluor...

Laser-induced fluorescence in malignant and normal tissue in mice injected with two different carotenoporphyrins

Nilsson, Henrik (författare)
Lund University Medical Laser Center, Lund Institute of Technology, Lund, Sweden
Johansson, Jonas (författare)
Lund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH,Lund University Medical Laser Center and Department of Physics, Lund Institute of Technology, Lund, Sweden
Svanberg, Katarina (författare)
Lund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH,Lund University Medical Laser Center, Lund Institute of Technology and the Department of Oncology, Lund University Hospital, Lund, Sweden
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Svanberg, Sune (författare)
Lund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH,Lund University Medical Laser Center and Department of Physics, Lund Institute of Technology, Lund, Sweden
Jori, G. (författare)
Department of Biology, Padova University, Padova, Italy
Reddi, E. (författare)
Department of Biology, Padova University, Padova, Italy
Segalla, A. (författare)
Department of Biology, Padova University, Padova, Italy
Gust, D. (författare)
Department of Chemistry and Biochemistry, Center for the Study of Early Events in Photosynthesis, Arizona State University, USA
Moore, A. L. (författare)
Department of Chemistry and Biochemistry, Center for the Study of Early Events in Photosynthesis, Arizona State University, USA
Moore, T. A. (författare)
Department of Chemistry and Biochemistry, Center for the Study of Early Events in Photosynthesis, Arizona State University, USA
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 (creator_code:org_t)
Springer Science and Business Media LLC, 1994
1994
Engelska.
Ingår i: British Journal of Cancer. - : Springer Science and Business Media LLC. - 0007-0920 .- 1532-1827. ; 70:5, s. 873-879
Relaterad länk:
https://www.nature.c...
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https://portal.resea... (primary) (free)
http://dx.doi.org/10...
https://urn.kb.se/re...
https://doi.org/10.1...
https://lup.lub.lu.s...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Laser-induced fluorescence (LIF) was used to characterise the localisation of an intravenously administered trimethylated carotenoporphyrin [CP(Me)3] and a trimethoxylated carotenoporphyrin [CP(OMe)3] in an intramuscularly transplanted malignant tumour (MS-2 fibrosarcoma) and healthy muscle in female Balb/c mice, 3, 24, 48 and 96 h post injection. The fluorescence was induced with a dye laser pumped by a nitrogen laser, emitting light at 425 nm. The fluorescence spectra were recorded in the region 455-760 nm using a polychromator equipped with an image-intensified CCD camera. The tumour/peritumoral muscle ratio was about 5:1 for CP(Me)3 and about 6:1 for CP(OMe)3 in terms of the background-free fluorescence intensity, which peaked at about 655 nm. By including the endogenous tissue fluorescence, the contrast was further enhanced by a factor of approximately 2.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

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MEDICINE
MEDICIN

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