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Evaluation of Autom...
Evaluation of Automatic Measurement of the Intracranial Volume Based on Quantitative MR Imaging
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- Ambarki, Khalid (författare)
- Umeå universitet,Radiofysik,Centrum för medicinsk teknik och fysik (CMTF),Umeå University, Sweden
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- Lindqvist, T. (författare)
- Umeå universitet,Diagnostisk radiologi,Centrum för medicinsk teknik och fysik (CMTF),Umeå University, Sweden
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- Wåhlin, Anders (författare)
- Umeå universitet,Radiofysik,Centrum för medicinsk teknik och fysik (CMTF),Umeå University, Sweden
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- Petterson, E. (författare)
- SyntheticMR ABE, Linköping, Sweden
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- Warntjes, Marcel Jan Bertus (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Klinisk fysiologi,Hälsouniversitetet,Fysiologiska kliniken US
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- Birgander, Richard (författare)
- Umeå universitet,Diagnostisk radiologi,Umeå University, Sweden
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- Malm, Jan (författare)
- Umeå universitet,Klinisk neurovetenskap,Umeå University, Sweden
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- Eklund, Anders (författare)
- Umeå universitet,Radiofysik,Centrum för medicinsk teknik och fysik (CMTF),Umeå University, Sweden Umeå University, Sweden
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(creator_code:org_t)
- American Society of Neuroradiology, 2012
- 2012
- Engelska.
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Ingår i: American Journal of Neuroradiology. - : American Society of Neuroradiology. - 0195-6108 .- 1936-959X. ; 33:10, s. 1951-1956
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- BACKGROUND AND PURPOSE: Brain size is commonly described in relation to ICV, whereby accurate assessment of this quantity is fundamental. Recently, an optimized MR sequence (QRAPMASTER) was developed for simultaneous quantification of T1, T2, and proton density. ICV can be measured automatically within minutes from QRAPMASTER outputs and a dedicated software, SyMRI. Automatic estimations of ICV were evaluated against the manual segmentation. MATERIALS AND METHODS: In 19 healthy subjects, manual segmentation of ICV was performed by 2 neuroradiologists (Obs1, Obs2) by using QBrain software and conventional T2-weighted images. The automatic segmentation from the QRAPMASTER output was performed by using SyMRI. Manual corrections of the automatic segmentation were performed (corrected-automatic) by Obs1 and Obs2, who were blinded from each other. Finally, the repeatability of the automatic method was evaluated in 6 additional healthy subjects, each having 6 repeated QRAPMASTER scans. The time required to measure ICV was recorded. RESULTS: No significant difference was found between reference and automatic (and corrected-automatic) ICV (P greater than .25). The mean difference between the reference and automatic measurement was -4.84 +/- 19.57 mL (or 0.31 +/- 1.35%). Mean differences between the reference and the corrected-automatic measurements were -0.47 +/- 17.95 mL (-0.01 +/- 1.24%) and -1.26 +/- 17.68 mL (-0.06 +/- 1.22%) for Obs1 and Obs2, respectively. The repeatability errors of the automatic and the corrected-automatic method were less than1%. The automatic method required 1 minute 11 seconds (SD = 12 seconds) of processing. Adding manual corrections required another 1 minute 32 seconds (SD = 38 seconds). CONCLUSIONS: Automatic and corrected-automatic quantification of ICV showed good agreement with the reference method. SyMRI software provided a fast and reproducible measure of ICV.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
Nyckelord
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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