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Moderate hyperkalem...
Moderate hyperkalemia in hospitalized patients with cirrhotic ascites indicates a poor prognosis
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- Wallerstedt, Sven, 1944 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine,Sahlgrenska University Hospital, Göteborg, Sweden
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- Simrén, Magnus, 1966 (författare)
- Sahlgrenska University Hospital, Göteborg, Sweden,Sahlgrenska universitetssjukhuset
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- Wahlin, Staffan (författare)
- Karolinska Institutet,Karolinska University Hospital Huddinge, Sweden
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- Lööf, Lars (författare)
- Uppsala universitet,Centrum för klinisk forskning, Västerås
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- Hultcrantz, Rolf (författare)
- Karolinska Institutet,Karolinska University Hospital, Solna, Sweden
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- Sjöberg, Klas (författare)
- Lund University,Lunds universitet,Gastroenterologi,Forskargrupper vid Lunds universitet,Gastroenterology,Lund University Research Groups,Skåne University Hospital, Malmö, Sweden
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- Sandberg Gertzen, Hanna (författare)
- University Hospital, Örebro, Sweden,Örebro läns landsting
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- Prytz, Hanne (författare)
- Skåne University Hospital, Lund, Sweden,Skånes universitetssjukhus (SUS)
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- Almer, Sven (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Gastroenterologi och hepatologi,Hälsouniversitetet,Magtarmmedicinska kliniken,Universitetssjukhuset i Linköping,Linköping University Hospital
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- Odén, Anders, 1942 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för matematiska vetenskaper, matematisk statistik,Department of Mathematical Sciences, Mathematical Statistics,Chalmers University, Gothenburg, Sweden
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(creator_code:org_t)
- 2013-01-08
- 2013
- Engelska.
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Ingår i: Scandinavian Journal of Gastroenterology. - : Informa Healthcare. - 0036-5521 .- 1502-7708. ; 48:3, s. 358-365
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Abstract
Ämnesord
Stäng
- Objective. Development of ascites in patients with liver cirrhosis is an ominous sign with a poor outcome. A liver transplantation must be considered, and it then becomes important to know if there are any factors indicating a worsened prognosis. Material and methods. We used official registers for a follow-up study of at least 5 years considering the prognosis of 155 prospectively recruited in-patients with cirrhotic ascites from medical units at nine Swedish university hospitals. All patients had undergone at least one diagnostic ascites tap, and had initially been questioned about background factors and physically examined according to a standardized case record form, followed by sampling of blood, urine, and ascites. Results. Death occurred within 1 year after inclusion in 53% of the cases, and was primarily liver-related in 70%. In a multivariable analysis, the two ordinary variables that showed the strongest correlation with risk of death were serum potassium and abdominal tenderness. All 22 patients with a serum potassium concentration of at least 4.8 mmol/L (maximum 5.8 mmol/L) died within 1 year after inclusion. Potassium concentration was related to renal function and potassium-saving drugs. Conclusion. This follow-up study of a prospectively recruited cohort of in-patients with cirrhotic ascites confirms their poor prognosis. Awareness of an elevated serum potassium value, which would reflect a threatened renal function, seems essential, because it may offer a simple way to identify cases with the worst prognosis. An area for further research should be to explore the significance of including serum potassium in prognostic models.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Nyckelord
- ascites
- cirrhosis
- potassium
- prognosis
- signs
- MEDICINE
- MEDICIN
- ascites
- cirrhosis
- potassium
- prognosis
- signs
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Wallerstedt, Sve ...
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Simrén, Magnus, ...
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Wahlin, Staffan
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Lööf, Lars
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Hultcrantz, Rolf
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Sjöberg, Klas
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visa fler...
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Sandberg Gertzen ...
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Prytz, Hanne
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Almer, Sven
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Odén, Anders, 19 ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Gastroenterologi
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Scandinavian Jou ...
- Av lärosätet
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Linköpings universitet
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Chalmers tekniska högskola
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Lunds universitet
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Göteborgs universitet
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Karolinska Institutet
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Uppsala universitet