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Reducing the stigma...
Reducing the stigma of long acting injectable antipsychotics : current concepts and future developments
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- Velaga, Sitaram (författare)
- Luleå tekniska universitet,Medicinsk vetenskap
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- Taylor, David M. (författare)
- Maudsley Hospital, Pharmacy Department
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- Werneke, Ursula (författare)
- Division of Psychiatry, Sunderby Research Unit, Department of Clinical Sciences, Umeå University
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(creator_code:org_t)
- 2018-12-14
- 2018
- Engelska.
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Ingår i: Conference proceedings of the 4th Masterclass Psychiatry. - : Taylor & Francis. ; , s. 30-33
- Relaterad länk:
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https://www.tandfonl...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Background: Long acting injectable antipsychotics (LAIAPs) are considered a major advance in psychiatric treatment concerning treatment adherence and outcomes. Yet, both, doctors and patients, remain sceptical.Aim: To explain the rationale for using LAI-APs, review their effectiveness and explore barriers to use. Method: Clinical overview of LAI-APs from the patient and doctor perspective.Results: LAI-APs were developed to increase adherence to treatment, thereby improving treatment outcomes. LAI-APs may reduce risk of relapse and hospitalization. Yet, the evidence from the few meta-analyses available remains weak. Both patients and doctors may associate LAI-APs with stigma and coercion. Current means of improving adherence include more focus on the therapeutic relationship, better information, adverse effects minimization and halflife extension of LAI-APs. Future means of improving adherence include novel administration techniques that abolish the need for injection.Conclusions: For both, clinicians and drug developers, drug adherence remains a major target for improving treatment outcomes.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Annan medicinteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Other Medical Engineering (hsv//eng)
Nyckelord
- Antipsychotics
- long-acting injections
- adherence
- relapse
- blood–brain barrier
Publikations- och innehållstyp
- ref (ämneskategori)
- kon (ämneskategori)