Hydrogen-bonding interactions in the 4-aminobenzoic acid salt of atenolol monohydrate

• Atenolol {or 4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl-acetamide} crystallizes with 4-aminobenzoic acid to give the salt {3-[4-(aminocarbonylmethyl)phenoxy]-2-hydroxypropy1}- isopropylammonium 4-aminobenzoate monohydrate, C14H23- N2O3*C7H6NO2-*H2O. In the crystal structure, the water molecule, the carboxylate group of 4-aminobenzoate, and the hydroxy and ether O atoms of atenolol form a supramolecular R33(11) heterosynthon. Three other types of supramolecular synthons link the asymmetric unit into a two-dimensional structure.

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