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The GRADE Working G...
The GRADE Working Group clarifies the construct of certainty of evidence
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- Hultcrantz, Monica (författare)
- Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU), S:t Eriksgatan 117, SE-102 33, Stockholm, Sweden; Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Tomtebodav. 18 A, SE-171 77, Stockholm, Sweden
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- Rind, David (författare)
- Institute for Clinical and Economic Review, Two Liberty Square, 9(th) Floor, Boston, MA 02109, USA; Harvard Medical School Beth Israel Deaconess Medical Center, 330 Brookline Avenue Boston, MA 02215, USA
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- Akl, Elie A. (författare)
- Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada; Department of Internal Medicine, American University of Beirut Medical Center, P.O. Box 11-0236, Riad-El-Solh, Beirut 1107 2020, Lebanon
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- Treweek, Shaun (författare)
- Health Services Research Unit, University of Aberdeen, 3rd Floor, Health Sciences Building, Foresterhill, Aberdeen, AB25 2ZD, UK
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- Mustafa, Reem A. (författare)
- Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada; Department of Medicine, Division of Nephrology and Hypertension, University of Kansas Medical Center, 3901 Rainbow Blvd, MS3002, Kansas City, KS 66160, USA
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- Iorio, Alfonso (författare)
- Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada; Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
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- Alper, Brian S. (författare)
- EBSCO Health, EBSCO Publishing, 10 Estes Street, Ipswich, MA, 01938 USA; Department of Family and Community Medicine, School of Medicine, University of Missouri-Columbia, One Hospital Drive, Columbia, MO 65212, USA
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- Meerpohl, Joerg J. (författare)
- Cochrane Germany, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Breisacher Strasse 153,79110 Freiburg, Germany; Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité - U1153, Inserm / Université Paris Descartes, Cochrane France
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- Murad, M. Hassan (författare)
- Mayo Clinic Evidence-based Practice Center, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
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- Ansari, Mohammed T. (författare)
- School of Epidemiology, Public Health and Preventive Medicine, Faculty of Medicine, University of Ottawa, 600 Peter Morand Crescent, Ottawa, Ontario K1G 5Z3, Canada
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- Katikireddi, Srinivasa Vittal (författare)
- MRC/CSO Social & Public Health Sciences Unit, University of Glasgow, 200 Renfield Street, Glasgow, G2 3QB, UK
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- Östlund, Pernilla (författare)
- Malmö högskola,Odontologiska fakulteten (OD),Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU), S:t Eriksgatan 117, SE-102 33, Stockholm, Sweden
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- Tranæus, Sofia (författare)
- Karolinska Institutet,Malmö högskola,Odontologiska fakulteten (OD),Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU), S:t Eriksgatan 117, SE-102 33, Stockholm, Sweden; Division of Cariology and Endodontology, Department of Dental Medicine, Karolinska institutet, Alfred Nobels Allé 8, SE-141 52, Huddinge, Sweden
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- Christensen, Robin (författare)
- Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Nordre Fasanvej 57, DK-2000 Copenhagen F, Denmark
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- Gartlehner, Gerald (författare)
- Danube University, Department for Evidence-based Medicine and Clinical Epidemiology, Dr. Karl Dorrekstrasse 30, 3500 Krems, Austria; RTI International, Research Triangle Park, 3040 East Cornwallis Rd, Research Triangle Park 27709, NC, USA
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- Brozek, Jan (författare)
- Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada; Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
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- Izcovich, Ariel (författare)
- Internal Medicine Service, German Hospital, Pueyrredón 1640, Buenos Aires C1118AAT, Argentina
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- Schünemann, Holger (författare)
- Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada; Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
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- Guyatt, Gordon (författare)
- Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada; Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
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Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU), S:t Eriksgatan 117, SE-102 33, Stockholm, Sweden; Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Tomtebodav 18 A, SE-171 77, Stockholm, Sweden Institute for Clinical and Economic Review, Two Liberty Square, 9(th) Floor, Boston, MA 02109, USA; Harvard Medical School Beth Israel Deaconess Medical Center, 330 Brookline Avenue Boston, MA 02215, USA (creator_code:org_t)
- Pergamon Press, 2017
- 2017
- Engelska.
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Ingår i: Journal of Clinical Epidemiology. - : Pergamon Press. - 0895-4356 .- 1878-5921. ; 87, s. 4-13
- Relaterad länk:
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https://doi.org/10.1...
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https://mau.diva-por... (primary) (Raw object)
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http://www.jclinepi....
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Objective: To clarify the grading of recommendations assessment, development and evaluation (GRADE) definition of certainty of evidence and suggest possible approaches to rating certainty of the evidence for systematic reviews, health technology assessments, and guidelines. Study Design and Setting: This work was carried out by a project group within the GRADE Working Group, through brainstorming and iterative refinement of ideas, using input from workshops, presentations, and discussions at GRADE Working Group meetings to produce this document, which constitutes official GRADE guidance. Results: Certainty of evidence is best considered as the certainty that a true effect lies on one side of a specified threshold or within a chosen range. We define possible approaches for choosing threshold or range. For guidelines, what we call a fully contextualized approach requires simultaneously considering all critical outcomes and their relative value. Less-contextualized approaches, more appropriate for systematic reviews and health technology assessments, include using specified ranges of magnitude of effect, for example, ranges of what we might consider no effect, trivial, small, moderate, or large effects. Conclusion: It is desirable for systematic review authors, guideline panelists, and health technology assessors to specify the threshold or ranges they are using when rating the certainty in evidence. (C) 2017 The Authors. Published by Elsevier Inc.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- GRADE
- Certainty of evidence
- Thresholds
- Guidelines
- Systematic reviews
- Health technology assessment
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Hultcrantz, Moni ...
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Rind, David
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Akl, Elie A.
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Treweek, Shaun
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Mustafa, Reem A.
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Iorio, Alfonso
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visa fler...
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Alper, Brian S.
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Meerpohl, Joerg ...
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Murad, M. Hassan
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Ansari, Mohammed ...
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Katikireddi, Sri ...
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Östlund, Pernill ...
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Tranæus, Sofia
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Christensen, Rob ...
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Gartlehner, Gera ...
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Brozek, Jan
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Izcovich, Ariel
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Schünemann, Holg ...
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Guyatt, Gordon
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Odontologi
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Journal of Clini ...
- Av lärosätet
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Malmö universitet
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Karolinska Institutet