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Open flap debrideme...
Open flap debridement of peri-implantitis with or without adjunctive systemic antibiotics : A randomized clinical trial
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- Hallström, Hadar (författare)
- Malmö högskola,Odontologiska fakulteten (OD),Centre for Oral Health Sciences Malmö, SWE,Malmö University
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- Persson, G. Rutger (författare)
- Department of Oral Health Sciences, School of Health and Society, Kristianstad University, Kristianstad, Sweden; Departments of Periodontics, and Oral Medicine, School of Dentistry, University of Washington, Seattle, WA, USA,Högskolan Kristianstad, SWE,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)
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- Lindgren, Susann (författare)
- Maxillofacial Unit, Halland's Hospital, Halmstad, Sweden,Central Hospital Halmstad,Hallands Sjukhus
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- Renvert, Stefan (författare)
- Blekinge Tekniska Högskola,Institutionen för hälsa,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)
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(creator_code:org_t)
- 2017-12-04
- 2017
- Engelska.
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Ingår i: Journal of Clinical Periodontology. - : John Wiley & Sons. - 0303-6979 .- 1600-051X. ; 44:12, s. 1285-1293
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Aims: To investigate clinical, radiographic and microbiological outcome over 12months following open flap debridement of peri-implantitis with or without antibiotics. Materials and methods: Peri-implantitis was surgically treated with or without Zithromax((R)) in 19 control and 20 test individuals. Probing pocket depth (PPD), gingival inflammation (BOP), intra-oral radiographs and microbial samples were studied. Per protocol and intent-to-treat analyses were performed. Results: The mean difference (reduction) in PPD values between baseline and month 12 in the test and control groups was 1.7mm (SD1.1, 95% CI: 1.1, 2.3, p<.001) and 1.6mm (SD +/- 1.5, 95% CI: 0.8, 2,4, p<.001), respectively. Data analysis failed to show study group differences for BOP, PPD, radiographic bone level and microbial load. Successful treatment (per protocol: PPD5mm, no BOP, no suppuration and no bone loss 0.5mm) at 12months in test and control groups was 7/15 (46.7%) and 4/16 (25.0%). Bacterial load reduction was similar in study groups with a temporary reduction following treatment. Conclusions: Surgical treatment of peri-implantitis with adjunctive systemic azithromycin did not provide 1-year clinical benefits in comparison with those only receiving open flap debridement.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- antibiotics
- microbiota
- peri-implantitis
- surgical treatment
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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