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Release of small hy...
Release of small hydrophilic molecules from polyelectrolyte capsules : Effect of the wall thickness
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- Cuomo, Francesca (författare)
- Univ Molise, Dipartimento Agr, Ambiente Alimenti DIAAA, I-86100 Campobasso, Italy
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- Lopez, Francesco (författare)
- Univ Molise, Dipartimento Agr, Ambiente Alimenti DIAAA, I-86100 Campobasso, Italy
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- Piludu, Marco (författare)
- Univ Cagliari, Dipartimento Sci Biomed, I-09042 Monserrato, CA, Italy
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- Miguel, Maria G. (författare)
- Univ Coimbra, Dept Chem, P-3004535 Coimbra, Portugal
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- Lindman, Björn (författare)
- Lund University,Lunds universitet,Mittuniversitetet,Avdelningen för kemiteknik,Lund Univ, Phys Chem, S-22100 Lund, Sweden,Fysikalisk kemi,Enheten för fysikalisk och teoretisk kemi,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Physical Chemistry,Physical and theoretical chemistry,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH
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- Ceglie, Andrea (författare)
- Univ Molise, Dipartimento Agr, Ambiente Alimenti DIAAA, I-86100 Campobasso, Italy
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(creator_code:org_t)
- Elsevier BV, 2015
- 2015
- Engelska.
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Ingår i: Journal of Colloid and Interface Science. - : Elsevier BV. - 0021-9797 .- 1095-7103. ; 447, s. 211-216
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Abstract
Ämnesord
Stäng
- Polymer nanocapsules assembled on cationic liposomes have been built through the layer-by-layer (LbL) technique. Chitosan and alginate, two biocompatible polyelectrolytes, were used to cover the template, where the Rhodamine B was previously loaded. The multishell formed with the alternate deposition of the polyelectrolytes, according to the principles of the LbL assembly, was supposed to change the permeability of the capsule wall. The thickness of the multishell was seen increasing with the number of layers deposited through the observations with the Transmission Electron Microscope. The permeability of the capsules was studied through Rhodamine B release assays. Nanocapsules with seven layers of polyelectrolytes released the dye slowly compared to the capsules with three or five layers. The Ritger-Peppas model was applied to investigate the release mechanisms and a non-Fickian transport behavior was detected regardless of the number of layers. Values of diffusion coefficients of Rhodamine B through the capsule wall were also calculated. (C) 2014 Elsevier Inc. All rights reserved.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Kemiteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Chemical Engineering (hsv//eng)
- NATURVETENSKAP -- Kemi -- Fysikalisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Physical Chemistry (hsv//eng)
Nyckelord
- Layer by layer
- Polyelectrolyte nanocapsules
- Multishell thickness
- Molecule release
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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