Perfluoroalkylated compounds in whole blood andplasma from the Swedish population

• The levels of five perfluoroalkylated (PFA) compounds, PFOS, PFOA, PFHxS, PFOSA andPFNA were determined in whole blood and plasma from 47 males and 36 femalesrepresenting the Swedish population. The analytical method developed and used includessolid-phase extraction and liquid chromatography electrospray masspectrometry. PFOS wasthe PFA found at the highest concentration in whole blood (18.2 pg/ul) followed by PFOSA(4.1 pg/μl), PFOA (2.7 pg/μl), PFHxS (2.3 pg/μl) and PFNA (0.3 pg/μl). Besides the fivecompounds determined, we were able to detect PFHxA, PFDA, PFDS, PFUnDA, PFDoDAand PFTDA in some of the samples/at low concentrations, the only compound included in thisstudy that we did not detect was PFBuS. This shows that the Swedish population are exposedfor a large number of PFAs. The concentrations of PFOS and PFOA correspond to thosefound in USA. The correlation between PFOS and the other compounds was studied in orderto find out if there is a common source of exposure. Only a very week correlation betweenPFOS and PFOA could be seen.

Ämnesord

NATURVETENSKAP  -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)

NATURAL SCIENCES  -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)

Nyckelord

National

Nationellt finansierad miljöövervakning

Hälsorelaterad miljöövervakning

Health

Biologiska mätdata - metaller

Biologiska mätdata - metaller

A Non-Toxic Environment

Giftfri miljö

Publikations- och innehållstyp

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