“Screening av PBDD/F i humana matriser”

• In a screening study during 2007-2008, also performed by MTM and commissioned bythe Swedish EPA, the presence of polybrominated dibenzo-p furans (PBDFs) weredetected in human adipose tissue from the Swedish population for the first time. In thisstudy ten additional adipose samples were analysed for polybrominated dibenzo-pdioxins and furans, PBDD/Fs. In all samples, 2,3,7,8-TeBDF was present in levelsranging from 0.23 to 0.54 pg g-1 lipid and pentabrominated furans were present in nineout of ten samples. The levels of 2,3,7,8-TeBDF, 1,2,3,7,8- and 2,3,4,7,8-PeBDF weresimilar to those reported in the previous screening study [1].By lowering the detection limits by using larger injection volumes by employing the PTVinjection technique, 2,3,7,8-TeBDD, 1,2,3,4,7,8-/1,2,3,6,7,8-HxBDD, 1,2,3,4,6,7,8-HpBDD, 1,2,3,4,7,8-HxBDF and 1,2,3,4,6,7,8-HpBDF were detected for the first time inhuman adipose tissue samples from Sweden. 2,3,7,8-TeBDD was detected in five out often samples in the range of 0.03-0.05 pg g-1 lipid. 2,3,7,8-TeBDD has been detected insamples with human origin earlier but not in samples from Sweden and levels of1,2,3,4,7,8-HxBDF has previously been detected in human milk samples from severalcountries, including Sweden. However, the detection of 1,2,3,4,7,8-/1,2,3,6,7,8-HxBDD,1,2,3,4,6,7,8-HpBDD and 1,2,3,4,6,7,8-HpBDF in human tissue is to our knowledgereported for the first time.To summarize, results from nineteen samples (the present and previous study)demonstrate the presence of brominated furans in the general Swedish population.Additionally, the individuals having the highest PBDD/F concentrations had also thehighest levels of PCDD/Fs (pg TEQ g-1). This might support the general assumption thatbrominated and chlorinated dioxins have the same sources and exposure routes.

Ämnesord

NATURVETENSKAP  -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)

NATURAL SCIENCES  -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)

Nyckelord

Nationellt finansierad miljöövervakning

National

Miljögiftssamordning

Toxic

Screening

Screening

A Non-Toxic Environment

Giftfri miljö

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vet (ämneskategori)

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