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Impact of Sex on Cl...
Impact of Sex on Clinical Outcomes in Patients undergoing Complex Percutaneous Coronary Angioplasty (from the e-ULTIMASTER Study)
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- Doolub, Gemina (författare)
- Keele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Keele, Newcastle, United Kingdom; Bristol Heart Institute, Bristol, United Kingdom
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- Tonino, Pim A. L. (författare)
- Catharina Hospital, Eindhoven, The Netherlands
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- Kedev, Sasko (författare)
- St. Cyril & Methodius University, Vodnjanska, Skopje, Macedonia
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- Monségu, Jacques (författare)
- Cardiovascular Institute, Groupe Hospitalier Mutualiste, Grenoble, France
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- Paradies, Valeria (författare)
- Department of Cardiology, Maasstad Hospital, Rotterdam, The Netherlands
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- Austin, David (författare)
- Academic Cardiovascular Unit, The James Cook University Hospital, Middlesbrough, United Kingdom
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- Spanó, Fabrizio (författare)
- Department of Cardiology, Meander Medical Center, Amersfoort, The Netherlands
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- Roffi, Marco (författare)
- Division of Cardiology, University Hospitals Geneva, Geneva, Switzerland
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- Fröbert, Ole, 1964- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper
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- von Birgelen, Clemens (författare)
- Thorax Centrum Twente, Medisch Spectrum Twente, Enschede, The Netherlands
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- Buchanan, Louise (författare)
- Cardiology Department, North Cumbria Integrated Care National Health Service Foundation Trust, Carlisle, United Kingdom
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- Mamas, Mamas A., Prof (författare)
- Keele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Keele, Newcastle, United Kingdom
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e-ULTIMASTER investigators, - (bidragsgivare)
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(creator_code:org_t)
- Elsevier, 2023
- 2023
- Engelska.
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Ingår i: American Journal of Cardiology. - : Elsevier. - 0002-9149 .- 1879-1913. ; 186, s. 71-79
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Female gender has been shown to be associated with worse clinical outcomes after percutaneous coronary intervention (PCI). However, the impact of gender on the clinical outcomes of complex PCI is still poorly understood. This study examined the differences in patient and coronary lesion characteristics and longer-term clinical outcomes in male and female patients who underwent complex PCI. This was a sub-analysis of the e-ULTIMASTER study, which was a large, multicontinental, prospective, observational study enrolling 37,198 patients who underwent PCI with the Ultimaster stent. Patients who underwent complex PCI were stratified by gender. The primary outcome was target lesion failure at 12 months, defined as the composite of cardiac death, target vessel-related myocardial infarction, and clinically driven target lesion revascularization at 12 months. A total of 13,623 patients underwent complex procedures, of which 35.7% were women. Women were twice as likely as men to be aged ≥80 years (17.6% vs 9%, p <0.0001) and had a higher prevalence of cardiovascular risk factors. Women had fewer lesions treated than men (1.5 ± 0.8 vs 1.6 ± 0.8, p <0.0001) and fewer stents implanted (2.0 ± 1.1 vs 2.1 ± 1.1, p <0.0001). There was no statistically significant difference in clinical outcomes at 12 months between women and men. Event rates were comparable in women and men for target lesion failure (4.7% vs 4.3%, p = 0.30), target vessel failure (5.1% vs 4.9%, p = 0.73), and cardiac death (1.8% vs 1.7%, p = 0.80).In conclusion, our findings suggest no significant differences in clinical outcomes between women and men who underwent complex PCI.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
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Till lärosätets databas
- Av författaren/redakt...
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Doolub, Gemina
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Tonino, Pim A. L ...
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Kedev, Sasko
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Monségu, Jacques
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Paradies, Valeri ...
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Austin, David
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visa fler...
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Spanó, Fabrizio
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Roffi, Marco
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Fröbert, Ole, 19 ...
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von Birgelen, Cl ...
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Buchanan, Louise
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Mamas, Mamas A., ...
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e-ULTIMASTER inv ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
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American Journal ...
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Örebro universitet