Atrial function after epicardial microwave ablation in patients with atrial fibrillation

• OBJECTIVES: To study epicardial microwave ablation of concomitant atrial fibrillation and its effects on heart rhythm and atrial function during follow-up. DESIGN: The study included 20 open-heart surgery patients with concomitant atrial fibrillation. Transthoracic echocardiography with flow and tissue Doppler recordings was performed preoperatively and at 6 months postoperatively. Blood samples were obtained preoperatively and postoperatively for analysis of atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and amino terminal precursor of brain natriuretic peptide (NT-proBNP). RESULTS: Fourteen of 19 patients (74%) were in sinus rhythm with no antiarrhythmic drugs at 12 months. All patients in sinus rhythm had preserved left and right atrial-filling waves through atrioventricular valves during atrial contraction. Tissue velocity echocardiography on patients in sinus rhythm showed preserved atrial wall velocities, atrial strain, and atrial strain rate. Levels of natriuretic peptides tended to decrease in patients with stable sinus rhythm at one year compared to patients in atrial fibrillation. CONCLUSIONS: Epicardial microwave ablation results in sinus rhythm in a majority of patients and seems to preserve atrial mechanical function

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)

Nyckelord

Aged

Atrial Fibrillation/metabolism/physiopathology/*surgery/ultrasonography

Atrial Function

Atrial Natriuretic Factor/blood

Biological Markers/blood

Catheter Ablation/adverse effects/*methods

Echocardiography; Doppler

Female

Heart Conduction System/*physiopathology

Humans

Male

Microwaves/*therapeutic use

Middle Aged

Myocardial Contraction

Natriuretic Peptide; Brain/blood

Peptide Fragments/blood

Pericardium/*surgery

Prospective Studies

Time Factors

Treatment Outcome

MEDICINE

MEDICIN

Surgery

Kirurgi

Kirurgi

Surgery

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)