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Consanguineous marr...
Consanguineous marriage, prepregnancy maternal characteristics and stillbirth risk : a population-based case-control study
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- Maghsoudlou, Siavash (författare)
- Karolinska Institutet
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- Cnattingius, Sven (författare)
- Karolinska Institutet
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- Aarabi, Mohsen (författare)
- Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran,Mazandaran Univ Med Sci, Fac Med, Sari, Iran.
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- Montgomery, Scott M., 1961- (författare)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Region Örebro län,Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institute, Karolinska Hospital, Stockholm, Sweden; Research Department of Epidemiology and Public Health, University College London, London, United Kingdom,Clinical Epidemiology and Biostatistics,Karolinska Inst, Dept Med Solna, Clin Epidemiol Unit, S-17176 Stockholm, Sweden.;Orebro Univ Hosp, Clin Epidemiol & Biostat, Orebro, Sweden.;Univ Orebro, SE-70182 Orebro, Sweden.;UCL, Res Dept Epidemiol & Publ Hlth, London, England.
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- Semnani, Shahriar (författare)
- Karolinska Institutet
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- Stephansson, Olof (författare)
- Karolinska Institutet
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- Wikström, Anna-Karin (författare)
- Karolinska Institutet,Uppsala universitet,Obstetrik & gynekologi,Karolinska Inst, Dept Med Solna, Clin Epidemiol Unit, S-17176 Stockholm, Sweden.
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- Bahmanyar, Shahram (författare)
- Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran; Clinical Epidemiology Unit, Center for Pharmacoepidemiology, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden,Golestan Univ Med Sci, Fac Med, Gorgan, Scandinavia.;Karolinska Inst, Clin Epidemiol Unit, S-17176 Stockholm, Sweden.;Karolinska Inst, Ctr Pharmacoepidemiol, Dept Med, S-17176 Stockholm, Sweden.
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(creator_code:org_t)
- 2015-07-07
- 2015
- Engelska.
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Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - : Wiley-Blackwell. - 0001-6349 .- 1600-0412. ; 94:10, s. 1095-1101
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Introduction: Consanguineous marriage is associated with increased risks for congenital anomalies, low birthweight, and other adverse perinatal outcomes. In this population-based, case-control study we investigated the association between consanguineous marriage (first-cousin marriage) and stillbirth risk, using prospectively collected information from prepregnancy visits.Material and methods: From 2007 to 2009, we identified 283 stillbirths (cases) and 2088 randomly selected live control births through prepregnancy visits in rural Golestan, Iran. The associations between consanguinity and prepregnancy maternal characteristics and stillbirth risk were examined using multivariate logistic regression.Results: The rate of consanguineous marriage was 19.4% among cases and 13.6% among controls. Consanguinity was associated with increased stillbirth risk [ odds ratio (OR) 1.53; 95% CI 1.10-2.14]. The association was significantly increased for preterm stillbirth (< 37 gestational weeks) (OR 2.43; 95% CI 1.46-4.04) but not for term stillbirth (>= 37 weeks) (OR 1.14; 95% CI 0.75-1.74). Low and high maternal age, underweight, obesity, nulliparity, a history of infertility or miscarriage, previous obstetric complications (preeclampsia, preterm delivery, and stillbirth in previous pregnancies) were also associated with increased stillbirth risks.Conclusions: Consanguineous marriage is associated with increased risk of stillbirth, particularly preterm stillbirth. Findings for other maternal risk factors for stillbirth in rural Iran are consistent with previously reported findings from high-income countries.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Nyckelord
- Adverse pregnancy outcome
- consanguineous marriage
- consanguinity
- cousin marriage
- Golestan province
- Iran
- maternal characteristics
- stillbirth
- Obstetrics and Gynaecology
- Obstetrik och gynekologi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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