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The effect of prehe...
The effect of preheated versus room-temperature skin disinfection on bacterial colonization during pacemaker device implantation : a randomized controlled non-inferiority trial
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- Wistrand, Camilla, 1970- (författare)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Department of Cardiothoracic surgery and Vascular surgery, Örebro University Hospital, Örebro, Sweden,Perioperative nursing
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- Söderquist, Bo, 1955- (författare)
- Örebro universitet,Institutionen för läkarutbildning,Inflammatory Response and Infection Susceptibility Centre (iRiSC) och Perioperative nursing
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- Magnusson, Anders (författare)
- Clinical Epidemiology and Biostatistics
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- Nilsson, Ulrica, 1960- (författare)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Perioperativ omvårdnad
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(creator_code:org_t)
- 2015-11-03
- 2015
- Engelska.
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Ingår i: Antimicrobial Resistance and Infection Control. - London, United Kingdom : BioMed Central (BMC). - 2047-2994. ; 4
- Relaterad länk:
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https://doi.org/10.1...
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https://aricjournal....
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: In clinical practice, patients who are awake often comment that cold surgical skin disinfectant is unpleasant. This is not only a problem of patients’ experience; heat loss during the disinfection process is a problem that can result in hypothermia. Evidence for the efficacy of preheated disinfection is scarce. We tested whether preheated skin disinfectant was non-inferior to room-temperature skin disinfectant on reducing bacterial colonization during pacemaker implantation.Methods: This randomized, controlled, non-inferiority trial included 220 patients allocated to skin disinfection with preheated (36 °C) or room-temperature (20 °C) chlorhexidine solution in 70 % ethanol. Cultures were obtained by swabbing at 4 time-points; 1) before skin disinfection (skin surface), 2) after skin disinfection (skin surface), 3) after the incision (subcutaneously in the wound), and 4) before suturing (subcutaneously in the wound).Results: The absolute difference in growth between patients treated with preheated versus room-temperature skin disinfectant was zero (90 % CI −0.101 to 0.101; preheated: 30 of 105 [28.6 %] vs. room-temperature: 32 of 112 [28.6 %]). The pre-specified margin for statistical non-inferiority in the protocol was set at 10 % for the preheated disinfectant. There were no significant differences between groups regarding SSIs three month postoperatively, which occurred in 0.9 % (1 of 108) treated with preheated and 1.8 % (2 of 112) treated with room-temperature skin disinfectant.Conclusion: Preheated skin disinfection is non-inferior to room-temperature disinfection in bacterial reduction. We therefore suggest that preheated skin disinfection become routine in clean surgery.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
Nyckelord
- Perioperative
- Skin disinfection
- Bacterial growth
- Non-inferiority
- Caring Sciences w. Medical Focus
- Omvårdnadsforskning med medicinsk inriktning
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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