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Prenatal phthalate ...
Prenatal phthalate exposure was associated with croup in Swedish infants
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- Shu, Huan, 1980- (författare)
- Karlstad University,Karlstads universitet,Institutionen för hälsovetenskaper (from 2013)
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- Wikström, Sverre, 1978- (författare)
- Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,School of Medical Sciences, Örebro University, Örebro, Sweden
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- Jönsson, Bo A.G. (författare)
- Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine
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- Lindh, Christian H. (författare)
- Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine
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- Svensson, Åke (författare)
- Lund University,Lunds universitet,Dermatologi,Forskargrupper vid Lunds universitet,Dermatology,Lund University Research Groups
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- Nånberg, Eewa (författare)
- Karlstad University,Karlstads universitet,Institutionen för hälsovetenskaper (from 2013)
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- Bornehag, Carl-Gustaf, 1957- (författare)
- Karlstad University,Karlstads universitet,Institutionen för hälsovetenskaper (from 2013),Avdelningen för hälsa och miljö,Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA
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(creator_code:org_t)
- 2018-02-22
- 2018
- Engelska.
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Ingår i: Acta Paediatrica. - : John Wiley & Sons. - 0803-5253 .- 1651-2227. ; 107:6, s. 1011-1019
- Relaterad länk:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- AIM: This study examined whether prenatal phthalate exposure was associated with lower or upper airway inflammation in infants.METHODS: From 2007-2010 we used liquid chromatography tandem mass spectrometry, adjusted for creatinine, to analyse 14 phthalate metabolites and one phthalate replacement in the urine of 1,062 Swedish mothers at a median of 10 weeks of pregnancy. This was used to determine any associations between prenatal phthalate exposure and croup, wheezing or otitis in their offspring until 12 months of age, using logistic regression, adjusted for potential confounders.RESULTS: There were significant associations between phthalate metabolites of butyl-benzyl phthalate (BBzP) and di-ethyl-hexyl phthalate (DEHP) concentrations in maternal prenatal urine and croup in 1,062 infants during the first year of life, when adjusted for potential confounders. A dose response relationship was found between prenatal phthalates exposure and maternal reported croup in the children, with a significant association in boys. There was no clear indication with regard to associations between prenatal phthalate exposure and wheezing or otitis media in the children during the first year of life.CONCLUSION: Our analysis suggests that exposure to BBzP and DEHP phthalates was associated with maternal reports of croup in infants up to 12 months of age.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Nyckelord
- Croup
- Exposure
- Phthalate
- Pregnant
- SELMA study
- Public Health Science
- Biomedical Sciences
- Croup
- Exposure
- Phthalate
- Pregnant
- SELMA study
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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