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Nationwide Study on...
Nationwide Study on Treatment of Mycotic Thoracic Aortic Aneurysms
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- Sörelius, Karl, 1981- (författare)
- Uppsala University,Uppsala universitet,Kärlkirurgi,Uppsala Univ, Sweden
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- Wanhainen, Anders (författare)
- Uppsala University,Uppsala universitet,Umeå universitet,Kirurgi,Kärlkirurgi,Uppsala Univ, Sweden
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- Wahlgren, Carl-Magnus (författare)
- Karolinska Institutet,Karolinska Hosp, Sweden,Karolinska University Hospital
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- Langenskiöld, Marcus (författare)
- Unit of Vascular Surgery, Department of Hybrid and Interventional Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Hybrid & Intervent Surg, Unit Vasc Surg, Gothenburg, Sweden
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- Roos, Håkan (författare)
- Unit of Vascular Surgery, Department of Hybrid and Interventional Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Hybrid & Intervent Surg, Unit Vasc Surg, Gothenburg, Sweden
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- Resch, T. (författare)
- Lund University,Lunds universitet,Vaskulära sjukdomar - kliniska studier,Forskargrupper vid Lunds universitet,Vascular Diseases - Clinical Research,Lund University Research Groups
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- Vaccarino, R. (författare)
- Lund University,Lunds universitet,Vaskulära sjukdomar - kliniska studier,Forskargrupper vid Lunds universitet,Vascular Diseases - Clinical Research,Lund University Research Groups
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- Arvidsson, Bengt (författare)
- Linköping University,Linköpings universitet,Institutionen för medicin och hälsa,Medicinska fakulteten,Region Östergötland, Thorax-kärlkliniken i Östergötland
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- Gillgren, Peter (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Soder Sjukhuset, Sweden,Stockholm South General Hospital
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- Bilos, L. (författare)
- Department of Cardiothoracic and Vascular Surgery, Faculty of Medicine and Vascular Surgery, Örebro University Hospital, Örebro, Sweden,Orebro Univ Hosp, Fac Med & Vasc Surg, Dept Cardiothorac & Vasc Surg, Orebro, Sweden
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- Pirouzram, Artai, 1970- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiothoracic and Vascular Surgery,Orebro Univ Hosp, Fac Med & Vasc Surg, Dept Cardiothorac & Vasc Surg, Orebro, Sweden,Örebro University Hospital
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- Holsti, Mari, 1963- (författare)
- Umeå universitet,Kirurgi,Umea Univ Hosp, Dept Surg & Perioperat Sci Surg, Umea, Sweden,Norrland University Hospital
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- Mani, Kevin, 1975- (författare)
- Uppsala University,Uppsala universitet,Kärlkirurgi,Uppsala Univ, Sweden
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(creator_code:org_t)
- Saunders Elsevier, 2019
- 2019
- Engelska.
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Ingår i: European Journal of Vascular and Endovascular Surgery. - : Saunders Elsevier. - 1078-5884 .- 1532-2165. ; 57:2, s. 239-246
- Relaterad länk:
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http://www.ejves.com...
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Objective: Mycotic aortic aneurysms are rare, life threatening, and complex. This nationwide study aimed to assess outcome after repair of mycotic thoracic aortic aneurysms (MTAAs). Methods: Patients treated in Sweden for MTAAs between 2000 and 2016 were identified in the Swedish vascular registry (2010-16) and local patient registries (2000-09). Primary outcome was survival, and secondary outcomes included surgical strategy, rate of infection related complications (IRC), and re-operations. Results: Fifty-two patients (median age 71 +/- 8.1 years; 28 [54%] men, 13 [25%] ruptured) were identified (3.6% of all thoracic aortic aneurysm repairs in Sweden). Aneurysm location was aortic arch (n = 6; 11%), descending aorta (n = 42; 81%), and multiple locations (n = 4; 8%). Twenty-nine (56%) patients had positive cultures; the most prevalent agent was Staphylococcus aureus (n = 16; 31%). Operative techniques included thoracic endovascular aortic repair (TEVAR; n = 35 [67%]), fenestrated/branched TEVAR (n = 8; 15%), hybrid repair (n = 7; 14%), and open patch repair (n = 2; 4%). Survival was 92% (95% confidence interval [CI] 88-96) at 30 days, 88% (95% CI 84-93) at three months, 78% (73-84) at one year, and 71% (64-77) at five years. The mean follow up among survivors (> 90 days) was 45 months (range 4-216 months). Antibiotics were administered for a median of 15 weeks (range 0-220 weeks). IRCs occurred in nine patients (17%): sepsis (n = 3), graft infection (n = 3), recurrent mycotic aneurysm (n = 1), aorto-oesophageal/bronchial fistula (n = 2). Six (67%) IRCs were fatal; 80% occurred within the first year. Re-operations were performed in nine patients (17%). Conclusions: TEVAR was often used as treatment for MTAAs, with acceptable short- and long-term survival when compared with open cohorts in the literature. IRCs are of concern and warrant follow up and long-term antibiotic treatment.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Aneurysm
- Aorta
- Infected
- Mycotic
- Thoracic
- Treatment
- Aneurysm
- Aorta
- Infected
- Mycotic
- Thoracic
- Treatment
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Sörelius, Karl, ...
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Wanhainen, Ander ...
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Wahlgren, Carl-M ...
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Langenskiöld, Ma ...
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Roos, Håkan
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Resch, T.
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Vaccarino, R.
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Arvidsson, Bengt
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Gillgren, Peter
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Bilos, L.
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Pirouzram, Artai ...
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Holsti, Mari, 19 ...
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Mani, Kevin, 197 ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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European Journal ...
- Av lärosätet
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Örebro universitet
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Umeå universitet
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Uppsala universitet
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Karolinska Institutet
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Linköpings universitet
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Lunds universitet