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The Association of ...
The Association of Intracranial Pressure Monitoring and Mortality : A Propensity Score-Matched Cohort of Isolated Severe Blunt Traumatic Brain Injury
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- Ahl, Rebecka, 1987- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Surgery, Karolinska University Hospital, Stockholm, Sweden
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- Sarani, Babak (författare)
- Department of Surgery, Center for Trauma and Critical Care, George Washington University, Washington, USA
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- Sjölin, Gabriel, 1979- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Surgery, Division of Trauma and Emergency Surgery, Örebro University Hospital, Örebro, Sweden
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- Mohseni, Shahin, 1978- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Surgery
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(creator_code:org_t)
- Wolters Kluwer, 2019
- 2019
- Engelska.
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Ingår i: Journal of Emergencies, Trauma and Shock. - : Wolters Kluwer. - 0974-2700 .- 0974-519X. ; 12:1, s. 18-22
- Relaterad länk:
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https://doi.org/10.4...
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https://urn.kb.se/re...
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https://doi.org/10.4...
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Abstract
Ämnesord
Stäng
- Background: Intracranial pressure (ICP) monitoring in traumatic brain injury (TBI) is common. Yet, its efficacy varies between studies, and the actual effect on the outcome is debated. This study investigates the association of ICP monitoring and clinical outcome in patients with an isolated severe blunt TBI.Patients and Methods: Patients were recruited from the American College of Surgeons-Trauma Quality Improvement Program database during 2014. Inclusion criteria were limited to adult patients (>= 18 years) who had a sustained isolated severe intracranial injury (Abbreviated Injury Scale [AIS] head of >= 3 and Glasgow Coma Scale [GCS] of <= 8) following blunt trauma to the head. Patients with AIS score >0 for any extracranial body area were excluded. Patients' demographics, injury characteristics, interventions, and outcomes were collected for analysis. Patients receiving ICP monitoring were matched in a 1:1 ratio with controls who were not ICP monitored using propensity score matching.Results: A total of 3289 patients met inclusion criteria. Of these, 601 (18.3%) were ICP monitored. After propensity score matching, 557 pairs were available for analysis with a mean age of 44 (standard deviation 18) years and 80.2% of them were male. Median GCS on admission was 4[3,7], and a third of patients required neurosurgical intervention. There were no statistical differences in any variables included in the analysis between the ICP-monitored group and their matched counterparts. ICP-monitored patients required significantly longer intensive care unit and hospital length of stay and had an increased mortality risk with odds ratio of 1.6 (95% confidence interval: 1.1-2.5, P = 0.038).Conclusion: ICP monitoring is associated with increased in-hospital mortality in patients with an isolated severe TBI. Further investigation into which patients may benefit from this intervention is required.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Nyckelord
- Intracranial pressure monitoring
- mortality
- traumatic brain injury
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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