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Outcome and present...
Outcome and presentation of heart failure in breast cancer patients : Findings from a Swedish register-based study
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- Hedayati, E. (författare)
- Karolinska Institutet
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- Papakonstantinou, A. (författare)
- Karolinska Institutet
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- Gernaat, S. A. M. (författare)
- Karolinska Institutet
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- Altena, R. (författare)
- Karolinska Institutet
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- Brand, Judith, 1984- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden
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- Alfredsson, Joakim, 1962- (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
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- Bhoo-Pathy, N. (författare)
- fJulius Centre University of Malaya, Faculty of Medicine, University of Malaya, Lembah Pantai, Kuala Lumpur, Malaysia
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- Herrmann, J. (författare)
- Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, United States,Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA
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- Linde, C. (författare)
- Karolinska Institutet
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- Dahlström, Ulf, 1946- (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
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- Bergh, J. (författare)
- Karolinska Institutet
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- Hübbert, Laila, 1964- (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US,Transplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden
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(creator_code:org_t)
- 2019-07-22
- 2020
- Engelska.
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Ingår i: European Heart Journal - Quality of Care and Clinical Outcomes. - : Oxford University Press. - 2058-5225 .- 2058-1742. ; 6:2, s. 147-155
- Relaterad länk:
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https://europepmc.or...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Aims: Heart failure (HF) patients diagnosed with breast cancer (BC) may have a higher risk of death, and different HF presentation and treatment than patients without BC.Methods and results: A total of 14 998 women with incident HF (iHF) or prevalent HF (pHF) enrolled in the Swedish HF Registry within and after 1 month since HF diagnosis, respectively, between 2008 and 2013. Patients were linked with the National Patient-, Cancer-, and Cause-of-Death Registry. Two hundred and ninety-four iHF and 338 pHF patients with BC were age-matched to 1470 iHF and 1690 pHF patients without BC. Comorbidity and treatment characteristics were compared using the χ2 tests for categories. Cox proportional hazard models assessed the hazard ratio (HR) and 95% confidence intervals (95% CIs) of all-cause and cardiovascular mortality among HF patients with and without BC. In the pHF group, BC patients had less often myocardial infarction (21.6% vs. 28.6%, P < 0.01) and received less often aspirin (47.6% vs. 55.1%, P = 0.01), coronary revascularization (11.8% vs. 16.2%, P < 0.01), or device therapy (0.9% vs. 3.0%, P = 0.03). After median follow-up of 2 years, risk of all-cause mortality (iHF: HR = 1.04, 95% CI = 0.83-1.29 and pHF: HR = 0.94, 95% CI = 0.79-1.12), cardiovascular mortality (iHF: HR = 0.94, 95% CI = 0.71-1.24 and pHF: HR = 0.89, 95% CI = 0.71-1.10), and HF mortality (iHF: HR = 0.80, 95% CI = 0.34-1.90 and pHF: HR = 0.75, 95% CI = 0.43-1.29) were similar for patients with and without BC in the iHF and pHF groups.Conclusion: Risk of all-cause and cardiovascular mortality in HF patients did not differ by BC status. Differences in pre-existing myocardial infarction and HF treatment among pHF patients with and without BC may suggest differences in pathogenesis of HF.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Breast cancer
- Clinical presentation
- Epidemiology
- Heart failure
- Mortality
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Hedayati, E.
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Papakonstantinou ...
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Gernaat, S. A. M ...
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Altena, R.
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Brand, Judith, 1 ...
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Alfredsson, Joak ...
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Bhoo-Pathy, N.
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Herrmann, J.
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Linde, C.
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Dahlström, Ulf, ...
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Bergh, J.
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Hübbert, Laila, ...
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- MEDICIN OCH HÄLSOVETENSKAP
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och Klinisk medicin
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European Heart J ...
- Av lärosätet
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Örebro universitet
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Linköpings universitet
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Karolinska Institutet