Formation and Out-of-Equilibrium, High/Low State Switching of a Nitroaldol Dynamer in Neutral Aqueous Media

• The nitroaldol reaction is demonstrated as an efficient dynamic covalent reaction in phosphate buffers at neutral pH. Rapid equilibration was recorded with pyridine-based aldehydes, and dynamic oligomerization could be achieved, leading to nitroaldol dynamers of up to 17 repeating units. The dynamers were applied in a coherent stimuli-responsive molecular system in which larger dynamers transiently existed out-of-equilibrium in a neutral aqueous system rich in formaldehyde, controlled by nitromethane.

Ämnesord

NATURVETENSKAP  -- Kemi -- Organisk kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Organic Chemistry (hsv//eng)

Nyckelord

dynamers

formaldehyde

nitroaldol

stimuli response

systems chemistry

Chemical engineering

Chemical reactions

Chemistry

Covalent reaction

Molecular systems

Out of equilibrium

Phosphate buffers

Stimuli-responsive

Organic Chemistry

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)