Sökning: id:"swepub:oai:DiVA.org:sh-15817" >
Structural analysis...
Structural analysis of the lipopolysaccharide from nontypeable Haemophilus influenzae strain 1003
-
- Månsson, Martin (författare)
- Södertörns högskola,Avdelning Naturvetenskap,Karolinska Institutet
-
- Hood, D W (författare)
- John Radcliffe Hospital, Oxford, UK
-
- Li, J J (författare)
- National Research Council of Canada, Ottawa, Ontario, Canada
-
visa fler...
-
- Richards, J C (författare)
- National Research Council of Canada, Ottawa, Ontario, Canada
-
- Moxon, E R (författare)
- John Radcliffe Hospital, Oxford, UK
-
- Schweda, Elke K H (författare)
- Södertörns högskola,Avdelning Naturvetenskap,Karolinska Institutet
-
visa färre...
-
(creator_code:org_t)
- 2002-02-14
- 2002
- Engelska.
-
Ingår i: European Journal of Biochemistry. - : Wiley. - 0014-2956 .- 1432-1033. ; 269:3, s. 808-818
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- Structural analysis of the lipopolysaccharide (LPS) of nontypeable Haemophilus influenzae strain 1003 has been achieved by the application of high-field NMR techniques, ESI-MS. capillary electrophoresis coupled to ESI-MS. composition and linkage analyses on O-deacylated LPS and core oligosaccharide material. It was found that the LPS contains the common structural element of H. influenzae, L-alpha-D-Hepp-(1 --> 2)-[PEtn --> 6]-L-alpha-D-Hepp-(1 --> 3)-[beta-D-Glcp-(1 --> 4)]-L-alpha-D-Hepp-(1 --> 5)-[PP Etn --> 4]-alpha-Kdop-(2 --> 6)-Lipid A. in which the beta-D-Glcp residue is substituted by phosphocholine at O-6 and an acetyl group at O-4. A second acetyl group is located at O-3 of the distal heptose residue (HepIII). HepIII is chain elongated at O-2 by either a beta-D-Glcp residue (major), lactose or sialyllactose (minor, i.e. alpha-Neu5Ac-(2 --> 3)-beta-D-Galp-(1 --> 4)-beta-D-Glcp), where a third minor acetylation site was identified at the glucose residue. Disialylated species were also detected. In addition. a minor substitution of ester-linked glycine at HepIII and Kdo was observed.
Ämnesord
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas