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Structures and gene...
Structures and gene clusters of the closely related O-antigens of Escherichia coli O46 and O134, both containing D-glucuronoyl-D-allothreonine
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Perepelov, Andrei V. (författare)
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Wang, Quan (författare)
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Filatov, Andrei V. (författare)
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Xia, Xianghong (författare)
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Shashkov, Alexander S. (författare)
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- Weintraub, Andrej (författare)
- Karolinska Institutet
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- Widmalm, Göran (författare)
- Stockholms universitet,Institutionen för organisk kemi
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Wang, Lei (författare)
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Knirel, Yuriy A. (författare)
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(creator_code:org_t)
- Elsevier BV, 2015
- 2015
- Engelska.
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Ingår i: Carbohydrate Research. - : Elsevier BV. - 0008-6215 .- 1873-426X. ; 409, s. 20-24
- Relaterad länk:
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https://su.diva-port... (primary) (Raw object)
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http://su.diva-porta...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- The O-polysaccharides (O-antigens) were isolated by mild acid degradation of the lipopolysaccharide (LPS) of Escherichia coli O46 and O134. The structures of their linear tetrasaccharide repeating units were established by sugar analysis along with 1D and 2D H-1 and C-13 NMR spectroscopy: [GRAPHICS] where D-aThr indicates D-allothreonine and R indicates O-acetyl substitution (similar to 70% on aThr and similar to 15% on GalNAc) in E. coli O46 whereas the O-acetylation is absent in E. coli O134. Functions of genes in the essentially identical O-antigen gene clusters of E. coli O46 and O134 were tentatively assigned by a comparison with sequences in available databases and found to be in agreement with the O-polysaccharide structures established.
Ämnesord
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
Nyckelord
- Escherichia coli
- O-polysaccharide
- O-antigen
- Bacterial polysaccharide structure
- O-antigen gene cluster
- Allothreonine
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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